2'-溴-4-氯苯乙酮合成路线 （共 272 条）
反应条件
1.1: hydroxylamine hydrochloride / water; methanol / 25 °C 2.1: sodium tetrahydroborate / water; acetonitrile / 0.17 h / 25 °C 3.1: sodium hydride / N,N-dimethyl-formamide / 1 h / 0 °C 3.2: 18 h / 20 °C 4.1: C19H23BNO3(1-)*H(1+); borane-THF / 1,4-dioxane; tetrahydrofuran / 0 °C / |Inert atmosphere View Scheme
参考文献
Ou, Wenhua; Espinosa, Sandraliz; Melendez, Hector J.; Farre, Silvia M.; Alvarez, Jaime L.; Torres, Valerie; Martinez, Ileanne; Santiago, Kiara M.; Ortiz-Marciales, Margarita
Journal of Organic Chemistry, 2013 , vol. 78, # 11 p. 5314 - 5327
反应条件
pyridine in ethanol 1 h; Heating / reflux;
参考文献
Apogee Biotechnology Corporation
Patent: US2007/32531 A1, 2007 ;
Location in patent: Page/Page column 41 ;
US 20070032531 A1
反应条件
1: benzene / Heating 2: NaOEt / ethanol; CHCl3 3: benzene 4: aq. HCl, AcOH / Heating View Scheme
参考文献
Kuchar,M. et al.
Collection of Czechoslovak Chemical Communications, 1972 , vol. 37, p. 3950 - 3955
反应条件
1: NaN3 / ethanol; acetic acid; H2O / cooling 2: O2 / toluene / -63 °C / Photolysis View Scheme
参考文献
Singh, Pradeep N. D.; Mandel, Sarah M.; Robinson, Rachel M.; Zhu, Zhendong; Franz, Roberto; Ault, Bruce S.; Gudmundsdottir, Anna D.
Journal of Organic Chemistry, 2003 , vol. 68, # 21 p. 7951 - 7960
反应条件
benzene Erwaermen des Reaktionsprodukts mit methanol. KOH;
参考文献
Genge; Trivedi
Journal of the Indian Chemical Society, 1959 , vol. 36, p. 598
反应条件
boron trifluoride; silver carbonate T=15°C; 20 h;
参考文献
Giordano, Claudio; Castaldi, Graziano; Casagrande, Francesco; Abis, Luigi
Tetrahedron Letters, 1982 , vol. 23, # 13 p. 1385 - 1386
反应条件
potassium carbonate in methanol pH=11; 0.05 h; microwave irradiation;
参考文献
Kidwai; Venkataramanan; Dave
Journal of Heterocyclic Chemistry, 2002 , vol. 39, # 5 p. 1045 - 1047
反应条件
hydrogen bromide 1 h; Heating; Yields of byproduct given;
参考文献
Novikova, A. P.; Perova, N. M.; Egorova, L. G.; Bragina, E. I.
Chemistry of Heterocyclic Compounds (New York, NY, United States), 1991 , vol. 27, # 6 p. 666 - 668
Khimiya Geterotsiklicheskikh Soedinenii, 1991 , vol. 27, # 6 p. 843 - 846
反应条件
dimethyl sulfoxide 1.) r.t., 20 h; 2.) 100 deg C, 6 h;
参考文献
Dash, B.; Dora, E. K.; Panda, C. S.
Journal of the Indian Chemical Society, 1988 , vol. 65, p. 136 - 137
反应条件
dimethyl sulfoxide 1.) r.t., 20 h; 2.) 100 deg C, 6 h;
参考文献
Dash, B.; Dora, E. K.; Panda, C. S.
Journal of the Indian Chemical Society, 1988 , vol. 65, p. 136 - 137
