1: phenylacetylene With n-butyllithium in diethyl ether; hexane T=-70°C; 2: N,N-dimethyl-formamide in diethyl ether; hexane T=20°C; 0.5 h; Further stages.;
参考文献
Asikainen, Martta; Lewis, William; Blake, Alexander J.; Woodward, Simon
Tetrahedron Letters, 2010 , vol. 51, # 49 p. 6454 - 6456
diethyl ether; ethylmagnesium bromide man setzt Orthoameisensaeureester zu, setzt Eisessig hinzu, zersetzt mit Eiswasser und verseift das gebildete Acetal mit verd. Schwefelsaeure;
1: phenylacetylene With ethyl bromide; iodine; magnesium in tetrahydrofuran T=35°C; 2: (4-morpholinyl)methanone in tetrahydrofuran T=35°C; 0.5 h; 3: With hydrogenchloride in tetrahydrofuran; water T=20 - 25°C; 0.5 h; Temperature;
参考文献
Zanka, Atsuhiko
Organic Process Research and Development, 2000 , vol. 4, # 1 p. 46 - 48
