反应条件
1: 1) MeLi / 1) THF, Et2O, -78 deg C to -20 deg C, 2) -20 deg C to room temperature
2: 1) Bu3SnH, 2) I2 / 1) Pd(PPh3)4 / 1) THF, room temperature, 3.5 h, 2) CH2Cl2, 20 deg C
3: 1) butyllithium, CuI, 2) HMPA, 1-iodobutane / 1) hexane, Et2O, -78 deg C, 4.5 h, 2a) -78 deg C, 0.5 h, b) room temperature, 18 h
View Scheme
参考文献
Dabdoub, Miguel J.; Begnini, Mauro L.; Cassol, Tania M.; Guerrero, Palimecio G.; Silveira, Claudio C.
Tetrahedron Letters, 1995 , vol. 36, # 42 p. 7623 - 7626
