反应条件
1: 3-methoxy-aniline With boron trichloride in dichloromethane; tetrachloroethane, 1,1,2,2-
T=0°C; 0.25 h;
2: benzonitrile With AlCl3, aluminium chloride in dichloromethane; tetrachloroethane, 1,1,2,2-
T=20°C; 5.5 h;
3: With hydrogenchloride in dichloromethane; tetrachloroethane, 1,1,2,2-
T=0 - 80°C; 0.5 h;
参考文献
BRISTOL-MYERS SQUIBB COMPANY; ZHAO, Yufen; GAVAI, Ashvinikumar V.; GILL, Patrice; KIM, Soong-Hoon; FINK, Brian E.; CHEN, Libing; SAULNIER, Mark G.; HAN, Wen-Ching
Patent: WO2014/47397 A1, 2014 ;
Location in patent: Paragraph 00196 ;
