(S)-(+)-1-二甲氨基-2-丙醇合成路线 （共 13 条）
反应条件
hydrogen; Ru(OCOCH3)2((S)-2,2'-bis(diphenylphosphino)-1,1'-binaphthyl) in methanol
P=38000 Torr; 12 h; Ambient temperature; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Kitamura, M.; Ohkuma, T.; Inoue, S.; Sayo N.; Kumobayashi, H.; et al.
Journal of the American Chemical Society, 1988 , vol. 110, # 2 p. 629 - 631
反应条件
[Ru(p-cymene)I-(S)-binap]I; hydrogen in ethanol; dichloromethane
T=30°C; P=77228.3 Torr; 40 h;
参考文献
Mashima, Kazushi; Kusano, Koh-hei; Ohta, Tetsuo; Noyori, Ryoji; Takaya, Hidemasa
Journal of the Chemical Society, Chemical Communications, 1989 , # 17 p. 1208 - 1210
参考文献
Salford Ultrafine Chemicals and Research Ltd.
Patent: US6143933 A1, 2000 ;
反应条件
α-bromo-camphor-sulfonic acid-(π); ethyl acetate
optische Spaltung;
参考文献
Merck and Co.Inc.
Patent: US2118054 , 1935 ;
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Major; Bonnett
Journal of the American Chemical Society, 1935 , vol. 57, p. 2125
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Merck and Co.Inc.
Patent: US2189808 , 1937 ;
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
2 h; Heating;
参考文献
Brine, George A.; Boldt, Karl G.; Prakash, Doriswamy; Kotchmar, Dennis J.; Bondeson, Virginia C.; et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1991 , # 8 p. 1809 - 1814
反应条件
Novozyme(R) 435
T=40°C; 75 h; Enzymatic reaction;
参考文献
Hull, Jonathan D.; Scheinmann, Feodor; Turner, Nicholas J.
Tetrahedron Asymmetry, 2003 , vol. 14, # 5 p. 567 - 576
反应条件
Novozyme(R) 435
T=20°C; 70 h; Enzymatic reaction;
参考文献
Hull, Jonathan D.; Scheinmann, Feodor; Turner, Nicholas J.
Tetrahedron Asymmetry, 2003 , vol. 14, # 5 p. 567 - 576
反应条件
formic acid
24 h; Heating;
参考文献
Farmaco, Edizione Scientifica, 1983 , vol. 38, # 7 p. 514 - 520
反应条件
tetra-n-butylammonium tetrafluoroborate in N,N-dimethyl-formamide; isopropyl alcohol
Electrochemical reaction;
参考文献
Yadav, Ashok K.; Manju, Meera
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, 2006 , vol. 45, # 12 p. 2770 - 2772
反应条件
Lipase PS
T=20°C; 16 h; Enzymatic reaction; Title compound not separated from byproducts;
参考文献
Hull, Jonathan D.; Scheinmann, Feodor; Turner, Nicholas J.
Tetrahedron Asymmetry, 2003 , vol. 14, # 5 p. 567 - 576
