3- 氨基-5-氯-2-羧酸合成路线 （共 3 条）
反应条件
1: With ethanol; tin(ll) chloride
T=90°C; 3 h;
2: With hydrogenchloride; water
6 h; Heating / reflux;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/97805 A1, 2005 ;
Location in patent: Page/Page column 58 ;
参考文献
State of Oregon, Acting by and Through the Oregon State Board of Higher Education, Acting for and on Behalf of the Oregon Health Sciences University and the University of Oregon; Cocensys, Inc.
Patent: US5801183 A1, 1998 ;
US 5801183 A
反应条件
thionyl chloride
T=20 - 90°C; 24 h;
参考文献
ELI LILLY AND COMPANY
Patent: WO2005/97805 A1, 2005 ;
Location in patent: Page/Page column 58 ;
