6-(4-联苯基)-6-氧代己酸合成路线 （共 10 条）
反应条件
1: With aluminium trichloride in nitrobenzene T=5 - 20°C; 16 h; 2: With lithium hydroxide in tetrahydrofuran; water 2 h; 3: With hydrogenchloride in water
参考文献
H. Lundbeck A/S
Patent: US2005/154022 A1, 2005 ;
Location in patent: Page/Page column 7; 14 ;
US 20050154022 A1
参考文献
Journal of Pharmaceutical Sciences, , vol. 65, # 9 p. 1374 - 1380
反应条件
1: AlCl3 / CS2 2: Br2 / acetic acid 3: NaOH / xylene / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 7, p. 504 - 508
反应条件
sodium hydroxide in xylene Heating;
参考文献
Journal of Medicinal Chemistry, , vol. 7, p. 504 - 508
反应条件
1: AlCl3 / CS2 2: aq. NaOH / methanol / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 7, p. 504 - 508
反应条件
1: Br2 / acetic acid 2: NaOH / xylene / Heating View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 7, p. 504 - 508
反应条件
AlCl3, aluminium chloride; nitrobenzene T=20°C; Friedel Crafts acylation;
参考文献
Cisneros, Jose A.; Bjoerklund, Emmelie; Gonzalez-Gil, Ines; Hu, Yanling; Canales, Angeles; Medrano, Francisco J.; Romero, Antonio; Ortega-Gutierrez, Silvia; Fowler, Christopher J.; Lopez-Rodriguez, Maria L.
Journal of Medicinal Chemistry, 2012 , vol. 55, # 2 p. 824 - 836
反应条件
1: acetic anhydride / 4 h / Inert atmosphere; Reflux 2: AlCl3, aluminium chloride; nitrobenzene / 20 °C View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 55, # 2 p. 824 - 836
反应条件
triethylsilane; trifluoroacetic acid
T=55°C; 72 h;
参考文献
H. Lundbeck A/S
Patent: US2005/154022 A1, 2005 ;
Location in patent: Page/Page column 7; 14 ;
US 20050154022 A1
