2-((1,3-二氧代异吲哚啉-2-基)甲基)苯甲酸合成路线 （共 7 条）
反应条件
hydrazine in ethanol; N,N-dimethyl-formamide T=75°C; deprotection; 2 h;
参考文献
Sun, Jung-Hui; Daneker, Wayne F.
Synthetic Communications, 1998 , vol. 28, # 24 p. 4525 - 4530
反应条件
hydrazine hydrate in ethanol; N,N-dimethyl-formamide T=75°C;
参考文献
Niewiadomski, Sven; Beebeejaun, Zeenat; Denton, Helen; Smith, Terry K.; Morris, Richard J.; Wagner, Gerd K.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 15 p. 3488 - 3499
反应条件
1: in N,N-dimethyl-formamide
Reflux;
2: With acetic acid in N,N-dimethyl-formamide
T=20°C; 0.5 h;
参考文献
Niewiadomski, Sven; Beebeejaun, Zeenat; Denton, Helen; Smith, Terry K.; Morris, Richard J.; Wagner, Gerd K.
Organic and Biomolecular Chemistry, 2010 , vol. 8, # 15 p. 3488 - 3499
反应条件
formic acid; sulfuric acid
参考文献
Bornstein et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 83,85
反应条件
2: formic acid; concentrated sulfuric acid
View Scheme
参考文献
Bornstein et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 83,85
反应条件
1: dimethylformamide / 60 °C
2: formic acid; concentrated sulfuric acid
View Scheme
参考文献
Bornstein et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 83,85
反应条件
1: dimethylformamide / 60 °C
2: formic acid; concentrated sulfuric acid
View Scheme
参考文献
Bornstein et al.
Journal of the American Chemical Society, 1956 , vol. 78, p. 83,85
