3-甲基-4-硝基苯甲醚合成路线 （共 58 条）
参考文献
Giegrich; Eisele-Buehler; Hermann; Kvasyuk; Charubala; Pfleiderer
Nucleosides and Nucleotides, 1998 , vol. 17, # 9-11 p. 1987 - 1996
反应条件
1.1: NaOEt / diethyl ether; ethanol / 3 h / 20 °C 1.2: 67 percent / 30percent H2O2; 2M NaOH / H2O / 1 h / 20 °C / pH 9 2.1: 95 percent / Amberlyst-15 / 2 h / Heating View Scheme
参考文献
Cravotto; Giovenzana; Pilati; Sisti; Palmisano
Journal of Organic Chemistry, 2001 , vol. 66, # 25 p. 8447 - 8453
反应条件
1: 1) NaOMe 2) 30percentH2O2, 10N NaOH / 1) ether, 10h, reflux 2: SOCl2 / toluene; dimethylformamide / 1) r.t., overnight 2) 50 deg C 3: 1) NaH / 1) THF 2) toluene, DMF, overnight 4: 75 percent / NH4OH / methanol / 0.75 h / Ambient temperature 5: 90 percent / ammonium formate / 10percent Pd/C / methanol / 0.75 h / Ambient temperature View Scheme
参考文献
Modi, Sandeep P.; McComb, Todd; Zayed, Abdel-Hadi; Oglesby, R. Christopher; Archer, Sydney
Tetrahedron, 1990 , vol. 46, # 16 p. 5555 - 5562
反应条件
pyridine; potassium permanganate in water 6 h; Heating;
参考文献
Pavlidis; Perry
Synthetic Communications, 1994 , vol. 24, # 4 p. 533 - 548
参考文献
Schiemann
Chemische Berichte, 1929 , vol. 62, p. 1804
反应条件
1: With sodium ethanolate in diethyl ether; ethanol T=20°C; 3 h; 2: With sodium hydroxide in water T=20°C; pH=9; 1 h; Further stages.;
参考文献
Journal of Organic Chemistry, , vol. 66, # 25 p. 8447 - 8453
反应条件
1: tin (II)-chloride; hydrochloric acid 2: glacial acetic acid; sodium acetate View Scheme
参考文献
Haworth; Lapworth
Journal of the Chemical Society, 1923 , vol. 123, p. 2989
Journal of the Chemical Society, 1924 , vol. 125, p. 1305
反应条件
pyridine; hydrogenchloride; SnCl*2H2O 1) ethanol, reflux, 6 h; 2) heating, 2 h.; Yield given. Multistep reaction;
参考文献
Karimov, A.; Telezhenetskaya, M. V.; Yunusov, S. Yu.
Chemistry of Natural Compounds, 1982 , vol. 18, # 4 p. 466 - 472
Khimiya Prirodnykh Soedinenii, 1982 , vol. 18, # 4 p. 498 - 504
反应条件
1: 98.5 percent / H2 / PtO2 / propan-2-ol / 2327.2 Torr 2: 1) conc. H2SO4, NaNO2, 2) CuBr, HBr / 1) H2O, 0-10 deg C, 2) H2O View Scheme
参考文献
Carpenter et al.
Journal of Organic Chemistry, 1951 , vol. 16, p. 586,606
反应条件
1: 62 percent / sodium ethoxide / dimethylsulfoxide / 24 h / Ambient temperature 2: 78 percent / iron powder, conc. hydrochloric acid / methanol; H2O / 24 h / Heating 3: 77 percent / allyl methyl carbonate, dihydridotetrikis(triphenylphosphine)ruthenium(II) / toluene / 24 h / 100 °C View Scheme
参考文献
Izumi; Yokota
Journal of Heterocyclic Chemistry, 1992 , vol. 29, # 5 p. 1085 - 1090
