2-氯-1-(2-氟苯基)乙酮合成路线 (共 3 条)
反应条件
1: o-di-fluorobenzene With sec.-butyllithium in tetrahydrofuran; hexane
T=-60°C; 1 h;
2: With zinc(II) chloride in tetrahydrofuran; hexane
T=-60 - -10°C;
3: chloroacetyl chloride With copper(l) chloride in tetrahydrofuran; hexane
T=-10 - 20°C; Further stages.;
参考文献
Rosen, Jonathan; Steinhuebel, Dietrich; Palucki, Michael; Davies, Ian
Organic Letters, 2007 , vol. 9, # 4 p. 667 - 669
反应条件
potassium peroxymonosulfate; ammonium chloride in methanol
5 h; Reflux;
参考文献
Swamy, Peraka; Kumar, MacHarla Arun; Reddy, Marri Mahender; Narender, Nama
Chemistry Letters, 2012 , vol. 41, # 4 p. 432 - 434
反应条件
potassium peroxymonosulfate; ammonium chloride
T=20°C; 48 h;
参考文献
Swamy, Peraka; Kumar, MacHarla Arun; Reddy, Marri Mahender; Narender, Nama
Chemistry Letters, 2012 , vol. 41, # 4 p. 432 - 434