[6-(苄氧基)萘-2-基]甲醇合成路线 （共 3 条）
反应条件
1: 6-benzyloxynaphthalene-2-carboxylic acid methyl ester With diisobutylaluminium hydride in tetrahydrofuran
T=-70 - 20°C; 5 h;
2: methanol in tetrahydrofuran
参考文献
DR. REDDY'S LABORATORIES LTD.
Patent: WO2005/40102 A2, 2005 ;
Location in patent: Page/Page column 46-47 ;
WO 2005/040102 A2
反应条件
lithium aluminium tetrahydride in tetrahydrofuran
T=25°C; 3 h;
参考文献
Nguyen, Thoi D.; Leung, Ken C.-F.; Liong, Monty; Pentecost, Cari D.; Stoddart, J. Fraser; Zink, Jeffrey I.
Organic Letters, 2006 , vol. 8, # 15 p. 3363 - 3366
反应条件
1.1: sodium hydride / N,N-dimethyl-formamide; mineral oil / 0 °C
1.2: 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C
View Scheme
参考文献
Wood, Paul M.; Woo, L. W. Lawrence; Labrosse, Jean-Robert; Thomas, Mark P.; Mahon, Mary F.; Chander, Surinder K.; Purohit, Atul; Reed, Michael J.; Potter, Barry V. L.
ChemMedChem, 2010 , vol. 5, # 9 p. 1577 - 1593
