1: With palladium diacetate; xantphos in N-dodecane; butan-1-ol T=25°C; Suzuki-Miyaura Coupling; 1 h; Inert atmosphereGlovebox; 2: With cesium hydroxide monohydrate in N-dodecane; water; butan-1-ol T=25°C; Suzuki-Miyaura Coupling; Inert atmosphereGlovebox;

1: With methanol in tetrahydrofuran T=-78 - 20°C; Inert atmosphere; 2: With trifluoroacetic anhydride in tetrahydrofuran T=20°C; 0.333333 h; regioselective reaction;

iron(III) sulfide; dipotassium peroxodisulfate; trifluoroacetic acid in dichloromethane; water T=20°C; 40 h; regioselective reaction;

potassium tert-butylate T=110°C; 8 h;

1.1: sodium hydride / diethyl ether; N,N-dimethyl-formamide / 0 - 20 °C / Inert atmosphere 1.2: 4 h / 20 °C / Inert atmosphere 2.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / ethanol; water; toluene / 12 h / Inert atmosphere; Reflux View Scheme

1.1: n-butyllithium / tetrahydrofuran / 1 h / -78 °C / |Inert atmosphere; |Schlenk technique 1.2: -78 - 20 °C / |Inert atmosphere; |Schlenk technique 2.1: hydrogenchloride / water / 20 °C / |Inert atmosphere; |Schlenk technique 3.1: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene; ethanol / 20 h / |Inert atmosphere; |Schlenk technique; |Reflux View Scheme

tetrakis(triphenylphosphine) palladium(0); sodium carbonate in ethanol; water; toluene 20 h; Inert atmosphereSchlenk techniqueReflux;

1: hydrogenchloride / water / 20 °C / |Inert atmosphere; |Schlenk technique 2: tetrakis(triphenylphosphine) palladium(0); sodium carbonate / water; toluene; ethanol / 20 h / |Inert atmosphere; |Schlenk technique; |Reflux View Scheme