N-乙酰基-3-甲苯胺合成路线 （共 128 条）
反应条件
1: 75 percent / HNO3, conc. H2SO4 / 0.5 h / 0 °C 2: 1.) H2SO4, arsenic acid; 2.) H2 / 2.) 10percent Pd-C / 1.) 130 deg C, 18 h; 2.) EtOH, 7 d 3: 90 percent / (CH3CO)2O / 2 h / Ambient temperature 4: 90 percent / LiAlH4 / tetrahydrofuran / 0 °C 5: 68 percent / HNO3, H2SO4 / 1 h / 0 °C 6: 80 percent / SnCl2, HCl / 1 h / 100 °C View Scheme
参考文献
Lee; Hashimoto; Shudo; Okamoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1857 - 1859
反应条件
1: sulfuric acid; acetic acid; nitric acid / und Erhitzen des Reaktionsprodukts mit wss.Schwefelsaeure 2: Diazotization.Behandlung der Diazoniumsalz-Loesung mit NaNO2 und Kupfer(I)-kupfer(II)-sulfit View Scheme
参考文献
Hodgson; Heyworth
Journal of the Chemical Society, 1949 , p. 1624
参考文献
Piers,E. et al.
Canadian Journal of Chemistry, 1962 , vol. 40, p. 511 - 517
反应条件
sulfuric acid; nitric acid; acetic acid und Erhitzen des Reaktionsprodukts mit wss.Schwefelsaeure;
参考文献
McGookin; Swift
Journal of the Society of Chemical Industry, London, 1939 , vol. 58, p. 152
Full Text Show Details
Green; Day
Journal of the American Chemical Society, 1942 , vol. 64, p. 1167,1170
反应条件
sulfuric acid; nitric acid; acetic acid und Erhitzen des Reaktionsprodukts mit wss.Schwefelsaeure;
参考文献
McGookin; Swift
Journal of the Society of Chemical Industry, London, 1939 , vol. 58, p. 152
Full Text Show Details
Green; Day
Journal of the American Chemical Society, 1942 , vol. 64, p. 1167,1170
反应条件
nitric acid anschliessend man verseift die Acetylverbindung durch Kochen mit Salzsaeure;
参考文献
de Vries
Recueil des Travaux Chimiques des Pays-Bas, 1942 , vol. 61, p. 647,658
反应条件
Reaktion ueber mehrere Stufen;
参考文献
Mayer
Chemische Berichte, 1913 , vol. 46, p. 2585
反应条件
1: 75 percent / HNO3, conc. H2SO4 / 0.5 h / 0 °C 2: 1.) H2SO4, arsenic acid; 2.) H2 / 2.) 10percent Pd-C / 1.) 130 deg C, 18 h; 2.) EtOH, 7 d 3: 90 percent / (CH3CO)2O / 2 h / Ambient temperature 4: 90 percent / LiAlH4 / tetrahydrofuran / 0 °C 5: 68 percent / HNO3, H2SO4 / 1 h / 0 °C 6: 80 percent / SnCl2, HCl / 1 h / 100 °C 7: ethanol / 2 h View Scheme
参考文献
Lee; Hashimoto; Shudo; Okamoto
Chemical and Pharmaceutical Bulletin, 1982 , vol. 30, # 5 p. 1857 - 1859
反应条件
1: (i) (bromination), (ii) (hydrolysis) 2: (i) NaNO2, aq. HCl, (ii) /BRN= 3587244/, (iii) NaOH, EtOH View Scheme
参考文献
Nasipuri,D. et al.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1979 , p. 3034 - 3036
反应条件
potassium permanganate in water 1.5 h; Heating;
参考文献
Lee, Chang Kiu; Ahn, Yu Mi
Journal of Organic Chemistry, 1989 , vol. 54, # 15 p. 3744 - 3747
