2-(4-溴-2,6-二氟苯基)乙腈合成路线 (共 3 条)
反应条件
in dimethyl sulfoxide T=23°C; 3 h;
参考文献
GLAXOSMITHKLINE LLC; GHERGUROVICH, Jonathan, Michael; MOORE, Michael, Lee; PARRISH, Cynthia, Ann; RIDGERS, Lance, Howard; YU, Hongyi
Patent: WO2013/28447 A1, 2013 ;
Location in patent: Page/Page column 111 ;
反应条件
in ethanol 2 h; Heating / reflux;
参考文献
WO2005/123698 A1, ;
Page/Page column 78 ;
反应条件
sulfuric acid; water 3 h; Heating / reflux;
参考文献
WO2005/123698 A1, ;
Page/Page column 78 ;