(S)-(+)-1,2,3,4-四氢-1-萘酚合成路线 （共 60 条）
反应条件
triethylamine in hexane T=20°C; Acylation; 144 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 64, # 26 p. 9365 - 9373
反应条件
triethylamine in hexane T=20°C; Acylation; 14 h; Title compound not separated from byproducts;
参考文献
Journal of Organic Chemistry, , vol. 64, # 26 p. 9365 - 9373
反应条件
1: With CF3O3S(1-)*C45H39N2OPRh(1+); benzo[1,3,2]dioxaborole in tetrahydrofuran T=20°C; 2 h; Inert atmosphere; 2: With dihydrogen peroxide; sodium hydroxide in ethanol; water T=0 - 20°C; optical yield given as percent eeenantioselective reaction;
参考文献
Tetrahedron Asymmetry, , vol. 21, # 11-12 p. 1458 - 1473
反应条件
1: 1-hydroxy-1,2,3,4-tetrahydronaphthalene With (-)-Tetramisole; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=-78°C; Inert atmosphereMolecular sieveResolution of racemate; 2: chlorotris(4-methoxyphenyl)silane in tetrahydrofuran T=-78°C; 48 h; Inert atmosphereMolecular sieveResolution of racemate; enantioselective reaction;
参考文献
Akhani, Ravish K.; Moore, Maggie I.; Pribyl, Julia G.; Wiskur, Sheryl L.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2384 - 2396
反应条件
1: cis-4-hydroxy-3,4-dihydro-1-benzopyran With (-)-Tetramisole; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=-78°C; Inert atmosphereMolecular sieveResolution of racemate; 2: chlorotris(4-methoxyphenyl)silane in tetrahydrofuran T=-78°C; 48 h; Inert atmosphereMolecular sieveResolution of racemate; enantioselective reaction;
参考文献
Akhani, Ravish K.; Moore, Maggie I.; Pribyl, Julia G.; Wiskur, Sheryl L.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2384 - 2396
反应条件
1: 1-hydroxy-1,2,3,4-tetrahydronaphthalene With (-)-Tetramisole; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=-78°C; Inert atmosphereMolecular sieveResolution of racemate; 2: tris([1,1′-biphenyl]-4-yl)chlorosilane in tetrahydrofuran T=-78°C; 72 h; Inert atmosphereMolecular sieveResolution of racemate; enantioselective reaction;
参考文献
Akhani, Ravish K.; Moore, Maggie I.; Pribyl, Julia G.; Wiskur, Sheryl L.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2384 - 2396
反应条件
1: cis-4-hydroxy-3,4-dihydro-1-benzopyran With (-)-Tetramisole; N-ethyl-N,N-diisopropylamine in tetrahydrofuran T=-78°C; Inert atmosphereMolecular sieveResolution of racemate; 2: tris([1,1′-biphenyl]-4-yl)chlorosilane in tetrahydrofuran T=-78°C; 72 h; Inert atmosphereMolecular sieveResolution of racemate; enantioselective reaction;
参考文献
Akhani, Ravish K.; Moore, Maggie I.; Pribyl, Julia G.; Wiskur, Sheryl L.
Journal of Organic Chemistry, 2014 , vol. 79, # 6 p. 2384 - 2396
反应条件
Pseudomonas cepacia lipase in di-isopropyl ether T=30°C; Esterification; Racemate separation; 14 h; Title compound not separated from byproducts;
参考文献
Synlett, , # 2 p. 225 - 226
反应条件
lipase from Pseudomonas cepacia immobilized on ceramic in toluene T=40°C; 4 h;
参考文献
Monatshefte fur Chemie, , vol. 134, # 8 p. 1151 - 1157
反应条件
Pseudomonas cepacia lipase; 4 A molecular sieve; peracetylated-β-cyclodextrin in toluene T=40°C; 2 h; Title compound not separated from byproducts;
参考文献
Tetrahedron Asymmetry, , vol. 14, # 17 p. 2547 - 2555
