1.1: NaH / dimethylformamide / 1 h
1.2: 66 percent / dimethylformamide / 17.5 h / 0 - 20 °C
2.1: 72 percent / PPh3; imidazole; iodine / benzene / 0.83 h / Heating
View Scheme
参考文献
Thompson, Andrew M.; Delaney, Amy M.; Hamby, James M.; Schroeder, Mel C.; Spoon, Teresa A.; Crean, Sheila M.; Showalter, H. D. Hollis; Denny, William A.
Journal of Medicinal Chemistry, 2005 , vol. 48, # 14 p. 4628 - 4653