3-溴-5-(2-氧代吡咯烷-1-基)苯甲酸甲酯合成路线 （共 2 条）
反应条件
caesium carbonate; 9,9-dimethyl-4,5-bis(diphenyl-phosphino)xanthene; tris-(dibenzylideneacetone)dipalladium(0) in 1,4-dioxane
T=55°C; 120 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2004/111022 A1, 2004 ;
Location in patent: Page/Page column 18 ;
WO 2004/111022 A1
反应条件
sodium hydride in tetrahydrofuran
T=20°C; 2 h;
参考文献
GLAXO GROUP LIMITED
Patent: WO2004/50619 A1, 2004 ;
Location in patent: Page 20 ;
WO 2004/050619 A1
