2-(2-甲基苯基)-1H-吲哚合成路线 （共 19 条）
反应条件
Fischer indole synthesis;
参考文献
Tsuchimoto, Teruhisa; Matsubayashi, Hiromichi; Kaneko, Masayoshi; Nagase, Yuta; Miyamura, Takuhiro; Shirakawa, Eiji
Journal of the American Chemical Society, 2008 , vol. 130, # 47 p. 15823 - 15835
反应条件
air; copper diacetate; palladium diacetate; acetic acid
T=20°C; 12 h; regioselective reaction;
参考文献
Zhao, Jinlong; Zhang, Yuhong; Cheng, Kai
Journal of Organic Chemistry, 2008 , vol. 73, # 18 p. 7428 - 7431
反应条件
DiPPF; bis(dibenzylideneacetone)-palladium(0); sodium t-butanolate in 1,4-dioxane
20 h; Heating;
参考文献
Cho, Chan Sik; Kim, Jun Ho; Kim, Tae-Jeong; Shim, Sang Chul
Journal of Chemical Research, 2004 , # 9 p. 630 - 631
反应条件
1: bis(η4-1,5-cyclooctadiene)-di-μ-methoxy-diiridium(I); 4,4'-di-tert-butyl-2,2'-dipyridyl / tetrahydrofuran / 18 h / 80 °C / Inert atmosphere
2: sodium carbonate; tris-(o-tolyl)phosphine; bis(dibenzylideneacetone)-palladium(0) / tetrahydrofuran; water / 18 h / 20 °C / Inert atmosphere
View Scheme
参考文献
Robbins, Daniel W.; Hartwig, John F.
Organic Letters, 2012 , vol. 14, # 16 p. 4266 - 4269
反应条件
1: acetic acid / ethanol / 1 h / 80 °C
2: 1.48 g / polyphosphoric acid / 1 h / 120 °C
View Scheme
参考文献
So, Chau Ming; Lau, Chak Po; Kwong, Fuk Yee
Organic Letters, 2007 , vol. 9, # 15 p. 2795 - 2798
反应条件
1: PPh3 / CH2Cl2 / 0 - 20 °C
2: 14.2 g / SnCl2*2H2O / ethanol / 0.75 h / Heating
3: 82 percent / K3PO4*H2O; Pd(OAc)2; S-Phos / toluene / 4 h / 90 °C
View Scheme
参考文献
Fang, Yuan-Qing; Lautens, Mark
Organic Letters, 2005 , vol. 7, # 16 p. 3549 - 3552
反应条件
1: 14.2 g / SnCl2*2H2O / ethanol / 0.75 h / Heating
2: 82 percent / K3PO4*H2O; Pd(OAc)2; S-Phos / toluene / 4 h / 90 °C
View Scheme
参考文献
Fang, Yuan-Qing; Lautens, Mark
Organic Letters, 2005 , vol. 7, # 16 p. 3549 - 3552
反应条件
1: sodium sulfite / water / 5 h / 70 - 80 °C
2: palladium dichloride; silver(I) acetate; sulfuric acid / N,N-dimethyl-formamide; acetonitrile / 0.67 h / 100 °C / |Sealed tube; |Microwave irradiation
View Scheme
参考文献
Miao, Tao; Li, Pinhua; Wang, Guan-Wu; Wang, Lei
Chemistry - An Asian Journal, 2013 , vol. 8, # 12 p. 3185 - 3190
反应条件
ammonium cerium (IV) nitrate in methanol
4 h; Reflux;
参考文献
Xie, Yinjun; Zhao, Yingwei; Qian, Bo; Yang, Lei; Xia, Chungu; Huang, Hanmin
Angewandte Chemie - International Edition, 2011 , vol. 50, # 25 p. 5682 - 5686
