反应条件
1: 445 mg / SO2Cl2 / pyridine; CH2Cl2 / 1 h / -20 °C
2: dimethylformamide / 1.) 0 deg C, 1 h; 2.) r.t., 30 min
3: 30percent H2O2 / acetic acid / Ambient temperature
4: trimethyl phosphite / methanol / Ambient temperature
View Scheme
参考文献
KAPPA BIOSCIENCE AS; SKATTEBOL, Lars; AUKRUST, Inger Reidun; SANDBERG, Marcel; CAMPBELL, Neil
Patent: WO2010/34999 A1, 2010 ;
Location in patent: Page/Page column 11; 26 ;
