4-(2-酮基-3-甲基-1-苯并咪唑基)哌啶合成路线 （共 6 条）
反应条件
potassium hexamethylsilazane in tetrahydrofuran; dichloromethane; ethyl acetate; trifluoroacetic acid
反应条件
1: NH4HCO2 / Pt/C / ethanol / 20 °C 2: Et3N / CH2Cl2 / 20 °C 3: KHMDS / tetrahydrofuran 4: aq. NaOH / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 6 p. 1687 - 1691
反应条件
1: dimethylformamide / 60 °C 2: NH4HCO2 / Pt/C / ethanol / 20 °C 3: Et3N / CH2Cl2 / 20 °C 4: KHMDS / tetrahydrofuran 5: aq. NaOH / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 6 p. 1687 - 1691
反应条件
1: KHMDS / tetrahydrofuran 2: aq. NaOH / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 6 p. 1687 - 1691
反应条件
1: Et3N / CH2Cl2 / 20 °C 2: KHMDS / tetrahydrofuran 3: aq. NaOH / ethanol / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 15, # 6 p. 1687 - 1691
参考文献
Science Union et cie, Societe Francaise de Recherche Medicale
Patent: US4264613 A1, 1981 ;
US 4264613 A
