3-(1-吡咯烷甲基)-1H-吲哚合成路线 （共 5 条）
反应条件
1: With n-butyllithium in hexane; toluene
T=0 - 5°C; Inert atmosphere;
2: With diisobutylaluminium hydride in hexane; toluene
T=0 - 50°C; Inert atmosphere;
参考文献
Todd, Robert; Hossain, M. Mahmun
Synthesis, 2009 , # 11 art. no. M07508SS, p. 1846 - 1850
反应条件
in methanol
T=50°C; P=6000480 Torr; 96 h;
参考文献
Matsumoto, Kiyoshi; Uchida, Takane; Hashimoto, Shiro; Yonezawa, Yukie; Iida, Hirokazu; et al.
Heterocycles, 1993 , vol. 36, # 10 p. 2215 - 2220
反应条件
sodium tetrahydroborate in ethanol
3 h; Ambient temperature;
参考文献
Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721
反应条件
1: 96 percent / benzene / 2 h / Heating; removing the liberated water
2: 94 percent / sodium borohydride / ethanol / 3 h / Ambient temperature
View Scheme
参考文献
Moriya, Tamon; Hagio, Katsuaki; Yoneda, Naoto
Chemical and Pharmaceutical Bulletin, 1980 , vol. 28, # 6 p. 1711 - 1721
反应条件
potassium tert-butylate in tetrahydrofuran
2 h; Yield given. Yields of byproduct given. Title compound not separated from byproducts;
参考文献
Love, Brian E.; Nguyen, Binh T.
Synlett, 1998 , # 10 p. 1123 - 1125
