1 - 甲基-5 - 硝基-1H -苯并[D]咪唑合成路线 （共 18 条）
参考文献
Annali di Chimica (Rome, Italy), , vol. 48, p. 1349,1354
反应条件
sulfuric acid; nitric acid 1 h; Ambient temperature; Yield given. Yields of byproduct given;
参考文献
Bulletin des Societes Chimiques Belges, , vol. 105, # 4 p. 213 - 214
反应条件
1: With lithium diisopropyl amide in tetrahydrofuran; n-heptane; ethylbenzene T=-78°C; 1 h; 2: With N-chloro-succinimide in tetrahydrofuran; n-heptane; ethylbenzene T=20°C; 0.166667 h; Further stages.;
参考文献
Piersanti, Giovanni; Giorgi, Luca; Bartoccini, Francesca; Tarzia, Giorgio; Minetti, Patrizia; Gallo, Grazia; Giorgi, Fabrizio; Castorina, Massimo; Ghirardi, Orlando; Carminati, Paolo
Organic and Biomolecular Chemistry, 2007 , vol. 5, # 16 p. 2567 - 2571
反应条件
hydrogen; palladium 10 on activated carbon in ethanol T=20°C; 18 h;
参考文献
Deciphera Pharmaceuticals, LLC
Patent: US2008/90856 A1, 2008 ;
Location in patent: Page/Page column 46-47 ;
US 20080090856 A1
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 2 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 13 p. 3821 - 3830
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 2 h;
参考文献
Lee, Jeewoo; Tran, Phuong-Thao; Hoang, Van-Hai; Thorat, Shivaji A.; Kim, Sung Eun; Ann, Jihyae; Chang, Yu Jin; Nam, Dong Woo; Song, Hyundong; Mook-Jung, Inhee; Lee, Jiyoun
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3821 - 3830
反应条件
hydrogen; palladium 10 on activated carbon in methanol
参考文献
F2G LTD
Patent: WO2006/123145 A1, 2006 ;
Location in patent: Page/Page column 53 ;
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform
12 h; Ambient temperature;
参考文献
Kaiya, Toyo; Aoyama, Shinsuke; Kohda, Kohfuku
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 6 p. 625 - 630
