(9ci)-1-甲基-6-硝基-1H-苯并咪唑合成路线 （共 14 条）
反应条件
3-chloro-benzenecarboperoxoic acid in chloroform 12 h; Ambient temperature;
参考文献
Kaiya, Toyo; Aoyama, Shinsuke; Kohda, Kohfuku
Bioorganic and Medicinal Chemistry Letters, 1998 , vol. 8, # 6 p. 625 - 630
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 2 h;
参考文献
Bioorganic and Medicinal Chemistry, , vol. 21, # 13 p. 3821 - 3830
反应条件
palladium 10 on activated carbon; hydrogen in methanol T=20°C; 2 h;
参考文献
Lee, Jeewoo; Tran, Phuong-Thao; Hoang, Van-Hai; Thorat, Shivaji A.; Kim, Sung Eun; Ann, Jihyae; Chang, Yu Jin; Nam, Dong Woo; Song, Hyundong; Mook-Jung, Inhee; Lee, Jiyoun
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3821 - 3830
反应条件
hydrogen; palladium 10 on activated carbon in methanol
参考文献
F2G LTD
Patent: WO2006/123145 A1, 2006 ;
Location in patent: Page/Page column 53 ;
反应条件
hydrogen; palladium on activated charcoal in methanol P=150.01 Torr;
参考文献
Garcia, M. Angeles; Claramunt, Rosa M.; Solcan, Tomas; Milata, Viktor; Alkorta, Ibon; Elguero, Jose
Magnetic Resonance in Chemistry, 2009 , vol. 47, # 2 p. 100 - 104
反应条件
1: 5-nitrobenzimidazole With potassium hydroxide in acetone
T=0°C; 0.5 h;
2: methyl iodide in acetone
T=20°C; 3 h;
参考文献
F2G LTD
Patent: WO2006/123145 A1, 2006 ;
Location in patent: Page/Page column 53 ;
反应条件
sodium hydride in N,N-dimethyl-formamide
T=0 - 20°C; 1 h; Overall yield = 99 percent;
参考文献
Lee, Jeewoo; Tran, Phuong-Thao; Hoang, Van-Hai; Thorat, Shivaji A.; Kim, Sung Eun; Ann, Jihyae; Chang, Yu Jin; Nam, Dong Woo; Song, Hyundong; Mook-Jung, Inhee; Lee, Jiyoun
Bioorganic and Medicinal Chemistry, 2013 , vol. 21, # 13 p. 3821 - 3830
反应条件
hydrogenchloride in ethanol
T=80°C; 1.5 h;
参考文献
Lopez-Alvarado, Pilar; Avendano, Carmen; Menendez, J. Carlos
Heterocycles, 1991 , vol. 32, # 5 p. 1003 - 1012
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
Heating;
参考文献
Bergman, Jan; Sand, Peter
Tetrahedron Letters, 1984 , vol. 25, # 18 p. 1957 - 1960
反应条件
potassium tert-butylate in N,N-dimethyl-formamide
Heating;
参考文献
Bergman, Jan; Norrby, Per-Ola; Sand, Peter
Tetrahedron, 1990 , vol. 46, # 17 p. 6113 - 6124
