反应条件
1: 1.) diethyl phosphorocyanidate, Et3N, 2.) Et3N / 1.) DMF, 80 deg C, 2 min, 2.) DMF, 80 deg C, 2 h
2: 92 percent / Ba(OH)2*8H2O / ethanol; H2O / Ambient temperature
View Scheme
参考文献
Rosowsky, Andre; Forsch, Ronald; Uren, Jack; Wick, Michael
Journal of Medicinal Chemistry, 1981 , vol. 24, # 12 p. 1450 - 1455
