2-甲基吲哚-3-羧酸乙酯合成路线 （共 28 条）
反应条件
1: With potassium carbonate in 1,4-dioxane T=100°C; 8 h; 2: With copper(l) iodide in 1,4-dioxane T=20 - 120°C; 7 h;
参考文献
Wang, Xianxue; Liu, Jin; Guo, Han; Ma, Chao; Gao, Xiai; Zhou, Kang; Huang, Guosheng
Synthesis, 2012 , vol. 44, # 7 p. 1037 - 1042
反应条件
potassium chloride; oxygen; copper diacetate in methanol T=50°C; Chan-Lam Coupling;
参考文献
Bunescu, Ala; Wang, Qian; Zhu, Jieping
Synthesis (Germany), 2012 , vol. 44, # 24 art. no. SS-2012-Z0772-OP, p. 3811 - 3814
反应条件
1: 82 percent / TsOH / benzene / Heating 2: 73 percent / Et3N / Pd(OAc)2 / dimethylformamide / 8 h / 120 °C View Scheme
参考文献
Synthesis, , # 3 p. 215 - 218
反应条件
1: 70 percent / TsOH / benzene / Heating 2: 65 percent / Et3N, P(2-CH3C6H4)3 / Pd(OAc)2 / dimethylformamide / 120 °C View Scheme
参考文献
Synthesis, , # 3 p. 215 - 218
反应条件
1: ethyl acetoacetate With potassium tert-butylate in various solvent(s) 0.166667 h; 2: 2-fluoro-1-nitrobenzene in various solvent(s) T=65 - 70°C; 0.5 h; 3: With iron; acetic acid T=115°C;
参考文献
Organic Preparations and Procedures International, , vol. 34, # 5 p. 493 - 499
反应条件
iron; acetic acid 1 h; Reflux;
参考文献
European Journal of Organic Chemistry, , # 12 p. 2360 - 2365
反应条件
1: potassium carbonate / water; N,N-dimethyl-formamide / 20 °C 2: copper diacetate; caesium carbonate / N,N-dimethyl-formamide / 1 h / 125 °C View Scheme
参考文献
Chemistry - A European Journal, , vol. 16, # 48 p. 14281 - 14284
反应条件
1: potassium carbonate / dimethyl sulfoxide / 80 - 90 °C 2: iron; acetic acid / 1 h / Reflux View Scheme
参考文献
European Journal of Organic Chemistry, , # 12 p. 2360 - 2365
反应条件
sulfuric acid T=-5°C; 0.5 h;
参考文献
Mills, Keith; Khawaja, Ibtisam K. Al; Al-Saleh, Fowzia; Joule, John A.
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1981 , p. 636 - 641
反应条件
ammonia; sodium in diethyl ether 2 h; Heating;
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 636 - 641
