2-溴-1,3-二甲基-5-硝基苯合成路线 （共 12 条）
参考文献
Haning, Helmut; Schmidt, Gunter; Pernerstorfer, Josef; Bischoff, Hilmar; Schmeck, Carsten; Vohringen, Verena; Woltering, Michael; Kretschmer, Axel; Faeste, Christiane
Patent: US2003/203898 A1, 2003 ;
反应条件
hydrogenchloride; tin(ll) chloride
参考文献
Spitzer; Wheland
Journal of the American Chemical Society, 1940 , vol. 62, p. 2995,3001
反应条件
LiBr*H2O in N,N-dimethyl-formamide
Reflux;
参考文献
Pfizer Inc.
Patent: US2012/165343 A1, 2012 ;
Location in patent: Page/Page column 38 ;
反应条件
1: water; ammonia / 180 °C
2: Diazotization.Behandlung der Diazoniumsalz-Loesung mit CuBr
View Scheme
参考文献
Spitzer; Wheland
Journal of the American Chemical Society, 1940 , vol. 62, p. 2995,3001
反应条件
dihydrogen peroxide in methanol
T=0 - 20°C; 3 h;
参考文献
Kalypsys, Inc.
Patent: US2005/234046 A1, 2005 ;
Location in patent: Page/Page column 94 ;
US 20050234046 A1
反应条件
sulfuric acid; acetic acid; sodium nitrite
anschliessend Erwaermen mit Kupfer(I)-bromid und wss. Bromwasserstoffsaeure;
参考文献
van Berk et al.
Recueil des Travaux Chimiques des Pays-Bas, 1956 , vol. 75, p. 1137,1138, 1149
反应条件
sulfuric acid
Diazotization.Kochen der Diazoniumsalz-Loesung;
参考文献
Spitzer; Wheland
Journal of the American Chemical Society, 1940 , vol. 62, p. 2995,3001
反应条件
1: nitric acid
2: sulfuric acid
3: aq.-ethanolic H2SO4 / Diazotization.Kochen der Diazoniumsalz-Loesung
View Scheme
参考文献
Spitzer; Wheland
Journal of the American Chemical Society, 1940 , vol. 62, p. 2995,3001
反应条件
1: 66.4 percent / nitric acid / acetic acid / 0.27 h / Heating
2: 50 percent / conc. H2SO4 / 1 h / 50 °C
3: 1.) NaNO2, H2SO4, 2.) CuBr / H2O / 0 - 5 °C
View Scheme
参考文献
Leffek, Kenneth T.; Pruszynski, Przemyslaw
Canadian Journal of Chemistry, 1988 , vol. 66, p. 1454 - 1458
反应条件
1: 50 percent / conc. H2SO4 / 1 h / 50 °C
2: 1.) NaNO2, H2SO4, 2.) CuBr / H2O / 0 - 5 °C
View Scheme
参考文献
Leffek, Kenneth T.; Pruszynski, Przemyslaw
Canadian Journal of Chemistry, 1988 , vol. 66, p. 1454 - 1458
