1-(4-溴苯基)-1-乙醇合成路线 （共 105 条）
反应条件
hydrogenchloride in water T=20°C; 20 h;
参考文献
GALAPAGOS NV; MENET, Christel, Jeanne, Marie; BLANC, Javier; HODGES, Alastair, James; BURLI, Roland, Werner; BRECCIA, Perla; BLACKABY, Wesley, Peter; VAN ROMPAEY, Luc, Juliaan, Corina; FLETCHER, Stephen, Robert
Patent: WO2010/10184 A1, 2010 ;
Location in patent: Page/Page column 102 ;
WO 2010/010184 A1
反应条件
polymer-supported phenyliodine(III) diacetate; JandaJel-CH2O-TEMPO in 1,2-dichloro-ethane T=70°C; 12 h;
参考文献
Li, Huanrong; Guan, Bingtao; Wang, Wenjin; Xing, Dong; Fang, Zhao; Wan, Xiaobing; Yang, Liping; Shi, Zhangjie
Tetrahedron, 2007 , vol. 63, # 35 p. 8430 - 8434
反应条件
3 A molecular sieve; oxygen; sodium carbonate; Pd((-)-sparteine)2Cl2 in tert-butyl alcohol T=65°C; 24 h;
参考文献
Tan, Rong; Dong, Yan; Peng, Ming; Zheng, Weiguo; Yin, Donghong
Applied Catalysis A: General, 2013 , vol. 458, p. 1 - 10
反应条件
C50H42ClN2O3Ru in chloroform T=25°C; Molecular sieveResolution of racemate; Kinetics; enantioselective reaction;
参考文献
Mizoguchi, Hirotaka; Uchida, Tatsuya; Katsuki, Tsutomu
Angewandte Chemie - International Edition, 2014 , vol. 53, # 12 p. 3178 - 3182
Angew. Chem., 2014 , vol. 126, # 12 p. 3242 - 3246,5
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 72 h; Microbiological reaction; enantioselective reaction;
参考文献
Silva, Camila R.; Souza, Juliana C.; Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pelizzari, Vivian H.; Andrade, Leandro H.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 23 - 28
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 48 h; Microbiological reaction; enantioselective reaction;
参考文献
Silva, Camila R.; Souza, Juliana C.; Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pelizzari, Vivian H.; Andrade, Leandro H.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 23 - 28
反应条件
oxygen in 1,2-dichloro-ethane T=20°C;
参考文献
Bai, Xing-Feng; Gao, Guang; Zheng, Zhan-Jiang; Li, Fei; Lai, Guo-Qiao; Jiang, Kezhi; Li, Fuwei; Xu, Li-Wen
Synlett, 2011 , # 20 art. no. W20211ST, p. 3031 - 3035
反应条件
bacteria HK1D10 in N,N-dimethyl-formamide T=20°C; pH=7; 72 h; Microbiological reactionaq. phosphate buffer; enantioselective reaction;
参考文献
Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pellizari, Vivian H.; Andrade, Leandro H.
Marine Drugs, 2011 , vol. 9, # 5 p. 889 - 905
反应条件
in acetone T=25°C; 3 h;
参考文献
Tetrahedron Letters, , vol. 35, # 47 p. 8751 - 8754
反应条件
1: 1,8-diazabicyclo[5.4.0]undec-7-ene / dichloromethane / 24 h / 25 °C 2: iodine / neat (no solvent) / 2 h / 85 °C View Scheme
参考文献
Jereb, Marjan; Vrazic, Dejan
Organic and Biomolecular Chemistry, 2013 , vol. 11, # 12 p. 1978 - 1999
