1-(4-溴苯基)-1-乙醇合成路线 （共 105 条）
反应条件
lipase B from Candida antarctica in toluene T=70°C; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
Xia, Bo; Cheng, Guilin; Lin, Xianfu; Wu, Qi
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2917 - 2923
反应条件
in 1,4-dioxane; water 168 h; Reflux;
参考文献
Xu, Zhao-Bing; Qu, Jin
Chemistry - A European Journal, 2013 , vol. 19, # 1 p. 314 - 323
反应条件
lipase B from Candida antarctica in toluene T=70°C; 48 h; Resolution of racemateEnzymatic reaction;
参考文献
Xia, Bo; Cheng, Guilin; Lin, Xianfu; Wu, Qi
European Journal of Organic Chemistry, 2014 , vol. 2014, # 14 p. 2917 - 2923
反应条件
hydrogen bromide in benzene T=0 - 40°C; 0.333333 h; other solvent: toluene;
参考文献
Stein, Allan R.; Dawe, Robert D.; Sweet, James R.
Canadian Journal of Chemistry, 1985 , vol. 63, p. 3442 - 3448
反应条件
1,3-bis-(diphenylphosphino)propane; palladium diacetate; triethylamine T=90°C; P=15201 Torr; 12 h; ConcentrationPressure;
参考文献
CONSTELLATION PHARMACEUTICALS; ALBRECHT, Brian, K.; AUDIA, James, Edmund; COOK, Andrew; GAGNON, Alexandre; HARMANGE, Jean-christophe; NAVESCHUK, Christopher, G.
Patent: WO2013/75083 A1, 2013 ;
Location in patent: Paragraph 00243; 00245 ;
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 72 h; Microbiological reaction; enantioselective reaction;
参考文献
Silva, Camila R.; Souza, Juliana C.; Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pelizzari, Vivian H.; Andrade, Leandro H.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 23 - 28
反应条件
Arthrobacter atrocyaneus in N,N-dimethyl-formamide T=32°C; 48 h; Microbiological reaction; enantioselective reaction;
参考文献
Silva, Camila R.; Souza, Juliana C.; Araujo, Lidiane S.; Kagohara, Edna; Garcia, Thais P.; Pelizzari, Vivian H.; Andrade, Leandro H.
Journal of Molecular Catalysis B: Enzymatic, 2012 , vol. 83, p. 23 - 28
反应条件
Candida antartica lipase B in various solvent(s) T=40°C; P=67505.4 Torr; 2 h;
参考文献
Netto, Caterina G.C.M.; Andrade, Leandro H.; Toma, Henrique E.
Tetrahedron Asymmetry, 2009 , vol. 20, # 19 p. 2299 - 2304
反应条件
Escherichia coli BioH in hexane T=35°C; 28 h; Resolution of racemate; enantioselective reaction;
参考文献
Tetrahedron Letters, , vol. 51, # 48 p. 6360 - 6364
反应条件
lipase B from Candida antarctica in cyclohexane T=50°C; 1.25 h; Resolution of racemate; optical yield given as percent ee;
参考文献
Li, Xiang; Shi, Yi; Wang, Zhoujun; Zhang, Yahong; Tang, Yi
Journal of Catalysis, 2012 , vol. 288, p. 24 - 32
