5-(2-氯乙基)-3-苯基-1,2,4-恶二唑合成路线 （共 5 条）
参考文献
Palazzo,G. et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, # 2 p. 351 - 367
反应条件
in neat (no solvent)
T=80°C; 0.133333 h; Green chemistry;
参考文献
Tadikonda, Ramu; Nakka, Mangarao; Gajula, Mahaboob Basha; Rayavarapu, Srinuvasarao; Gollamudi, Padma Rao; Vidavalur, Siddaiah
Synthetic Communications, 2014 , vol. 44, # 13 p. 1978 - 1986
反应条件
hydrogenchloride; tin(IV) chloride
T=100°C; 2 h;
参考文献
Yarovenko; Taralashvili; Zavarzin; Krayushkin
Tetrahedron, 1990 , vol. 46, # 11 p. 3941 - 3952
反应条件
in toluene
2 h; RefluxMolecular sieve;
参考文献
Ozcan, Sevil; Kazi, Aslamuzzaman; Marsilio, Frank; Fang, Bin; Guida, Wayne C.; Koomen, John; Lawrence, Harshani R.; Sebti, Said M.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 10 p. 3783 - 3805
反应条件
1: K2CO3
2: toluene / Heating
View Scheme
参考文献
Palazzo,G. et al.
Journal of Medicinal and Pharmaceutical Chemistry, 1961 , vol. 4, # 2 p. 351 - 367
