5-溴-2-氯吡啶合成路线

参考文献

Morales-Ramos, Angel I.; Li, Yue H.; Hilfiker, Mark; Mecom, John S.; Eidam, Patrick; Shi, Dongchuan; Tseng, Pei-San; Brooks, Carl; Zhang, David; Wang, Ning; Jaworski, Jon-Paul; Morrow, Dwight; Fries, Harvey; Edwards, Richard; Jin, Jian
Bioorganic and Medicinal Chemistry Letters, 2011 , vol. 21, # 10 p. 2806 - 2811

123-90-0硫代吗啉+

53939-30-35-溴-2-氯吡啶

223556-42-14-(5-溴-2-吡啶基)硫代吗啉

参考文献

Endo, Hitoshi
Patent: EP1481965 A1, 2004 ;
Location in patent: Page 29 ;

53939-30-35-溴-2-氯吡啶

180916-06-75-溴-2-(2-吡咯烷o乙氧基)吡啶

参考文献

JANSSEN PHARMACEUTICA N.V.
Patent: WO2007/71646 A1, 2007 ;
Location in patent: Page/Page column 35 ;
WO 2007/071646 A1

53939-30-35-溴-2-氯吡啶

35235-74-66-溴四唑[1,5-A]砒啶

参考文献

Cmoch; Korczak; Stefaniak; Webb
Journal of Physical Organic Chemistry, 1999 , vol. 12, # 6 p. 470 - 478

53939-30-35-溴-2-氯吡啶

823221-93-85-溴-2-氯-4-三氟甲基吡啶

参考文献

Tetrahedron, , vol. 60, # 51 p. 11869 - 11874

53939-30-35-溴-2-氯吡啶+

67-63-0异丙醇

870521-31-65-溴-2-异丙氧基吡啶

参考文献

H. Lundbeck A/S; Eskildsen, Jørgen; Sams, Anette Graven; Püschl, Ask
Patent: US2013/12530 A1, 2013 ;
Location in patent: Paragraph 0170-0171 ;
US 20130012530 A1

53939-30-35-溴-2-氯吡啶+

683-60-3异丙醇钠

870521-31-65-溴-2-异丙氧基吡啶

参考文献

IRM LLC
Patent: WO2005/116000 A1, 2005 ;
Location in patent: Page/Page column 52 ;
WO 2005/116000 A1

53939-30-35-溴-2-氯吡啶

31301-51-62-氯-5-氟吡啶

参考文献

Yamada, Shigeyuki; Knochel, Paul
Synthesis, 2010 , # 14 art. no. T09010SS, p. 2490 - 2494

53939-30-35-溴-2-氯吡啶

874959-68-95-溴-2-吡啶磺酰氯

参考文献

WO2014/178 A1, ;

53939-30-35-溴-2-氯吡啶+

71-23-8丙醇

850142-79-95-溴-2-丙氧基吡啶

参考文献

H. Lundbeck A/S; Eskildsen, Jørgen; Sams, Anette Graven; Püschl, Ask
Patent: US2013/12530 A1, 2013 ;
Location in patent: Paragraph 0173 ;
US 20130012530 A1