5-溴-2-氯吡啶合成路线

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Raeth
Justus Liebigs Annalen der Chemie, 1931 , vol. 487, p. 105,115

参考文献

Coburn, Craig A.; Maletic, Milana; Soll, Richard; Li, Chunsing; Luo, Yunfu; Qi, Zhiqi
Patent: US2014/5103 A1, 2014 ;
Location in patent: Paragraph 0261; 0262 ;

53939-30-35-溴-2-氯吡啶

874959-69-02-苄基硫代-5-溴吡啶

参考文献

ASTRAZENECA AB
Patent: WO2008/2244 A2, 2008 ;
Location in patent: Page/Page column 71 ;
WO 2008/002244 A2

53939-30-35-溴-2-氯吡啶+

100-51-6苯甲醇

84611-43-82-氯-5-苄氧基吡啶

参考文献

Nara, Susheel J.; Jha, Mukund; Brinkhorst, Johan; Zemanek, Tony J.; Pratt, Derek A.
Journal of Organic Chemistry, 2008 , vol. 73, # 23 p. 9326 - 9333

53939-30-35-溴-2-氯吡啶+

37622-90-54-吡唑甲酸乙酯

915394-68-21-(5-溴-2-吡啶)-1H-吡唑-4-羧酸乙酯

参考文献

Warshakoon, Namal C.; Wu, Shengde; Boyer, Angelique; Kawamoto, Richard; Sheville, Justin; Bhatt, Ritu Tiku; Renock, Sean; Xu, Kevin; Pokross, Matthew; Zhou, Songtao; Walter, Richard; Mekel, Marlene; Evdokimov, Artem G.; East, Stephen
Bioorganic and Medicinal Chemistry Letters, 2006 , vol. 16, # 21 p. 5616 - 5620

616-45-52-吡咯烷酮+

53939-30-35-溴-2-氯吡啶

928775-04-61-(5-溴-2-吡啶基)-2-吡咯烷酮

参考文献

GLAXO GROUP LIMITED
Patent: WO2007/25596 A1, 2007 ;
Location in patent: Page/Page column 30 ;
WO 2007/025596 A1

109-04-6邻溴吡啶+

53939-30-35-溴-2-氯吡啶

93297-75-7

参考文献

Kuraray Co., Ltd.
Patent: EP2223912 A1, 2010 ;
Location in patent: Page/Page column 8 ;

109-09-12-氯吡啶+

53939-30-35-溴-2-氯吡啶

93297-75-7

参考文献

Kuraray Co., Ltd.
Patent: EP2223912 A1, 2010 ;
Location in patent: Page/Page column 9 ;

53939-30-35-溴-2-氯吡啶

93297-75-7

参考文献

Parry, Paul R.; Wang, Changsheng; Batsanov, Andrei S.; Bryce, Martin R.; Tarbit, Brian
Journal of Organic Chemistry, 2002 , vol. 67, # 21 p. 7541 - 7543

53939-30-35-溴-2-氯吡啶+

95-77-23.4-二氯苯酚

99902-96-2

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Markley; Tong; Dulworth; Steward; Goralski; Johnston; Wood; Vinogradoff; Bargar
Journal of Medicinal Chemistry, 1986 , vol. 29, # 3 p. 427 - 433