2,2,6-三甲基-4H-1,3-二英-4-酮合成路线 （共 203 条）
参考文献
Huggins, Michael T.; Barber, Patrick S.; Florian, David; Howton, William
Synthetic Communications, 2008 , vol. 38, # 23 p. 4226 - 4239
参考文献
Naylor
Journal of the Chemical Society, 1945 , p. 244
反应条件
0.0333333 h; microwave irradiation;
参考文献
Miriyala, Bruhaspathy; Williamson, John S.
Tetrahedron Letters, 2003 , vol. 44, # 43 p. 7957 - 7959
反应条件
T=120 - 130°C; 1.5 h;
参考文献
Chemical & Pharmaceutical Bulletin, , vol. 31, # 12 p. 4300 - 4305
反应条件
in toluene T=110 - 115°C; 3.5 h;
参考文献
Mck; Zazulak; Radov; baer; Steward; Elzer; Kinsolving; Georgiev
Journal of Medicinal Chemistry, 1988 , vol. 31, # 10 p. 1910 - 1918
反应条件
sodium acetate in tetrahydrofuran 24 h; Reflux;
参考文献
Sridharan, Vellaisamy; Ruiz, Miriam; Menendez, J. Carlos
Synthesis, 2010 , # 6 art. no. T12709SS, p. 1053 - 1057
反应条件
T=400°C; P=0.1 Torr; various substrates, competitive reactions; Product distribution;
参考文献
Birney, David M.; Xu, Xiaolian; Ham, Sihyun; Huang, Xiaomeng
Journal of Organic Chemistry, 1997 , vol. 62, # 21 p. 7114 - 7120
反应条件
1: 2,2,6-trimethyl-4H-1,3-dioxin-4-one With 3-hydroxy-propionitrile T=120°C; 3 h; oil bath; 2: 2,3-dichlorobenzylaldehyde; methyl 3-aminocrotonate in isopropyl alcohol T=20°C; Reflux; 3: With sodium hydroxide in dichloromethane T=20°C;
参考文献
ALPHORA RESEARCH INC.; SOUZA, Fabio; PAN, Ming
Patent: WO2011/130852 A1, 2011 ;
Location in patent: Page/Page column 6 ;
反应条件
in toluene 3 h; Heating;
参考文献
Reeve; Crout; Cooper; Fray
Tetrahedron Asymmetry, 1992 , vol. 3, # 6 p. 785 - 794
反应条件
sodium acetate in tetrahydrofuran 24 h; Reflux;
参考文献
Sridharan, Vellaisamy; Ruiz, Miriam; Menendez, J. Carlos
Synthesis, 2010 , # 6 art. no. T12709SS, p. 1053 - 1057
