Boc-alpha-甲基-d-苯丙氨酸合成路线 （共 17 条）
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / tetrahydrofuran / 3.5 h / 20 °C
2: methanol; caesium carbonate / 4 h / 20 °C
3: sodium periodate; ruthenium(III) chloride*(x)H2O / tetrachloromethane; water; acetonitrile / 8 h / 20 °C
View Scheme
参考文献
Sugiyama, Shigeo; Arai, Satoshi; Ishii, Keitaro
Tetrahedron, 2012 , vol. 68, # 38 p. 8033 - 8045
反应条件
1: methanol; caesium carbonate / 4 h / 20 °C
2: sodium periodate; ruthenium(III) chloride*(x)H2O / tetrachloromethane; water; acetonitrile / 8 h / 20 °C
View Scheme
参考文献
Sugiyama, Shigeo; Arai, Satoshi; Ishii, Keitaro
Tetrahedron, 2012 , vol. 68, # 38 p. 8033 - 8045
反应条件
1: 4-(N,N-dimethlyamino)pyridine; triethylamine / tetrahydrofuran / 3.5 h / 20 °C
2: methanol; caesium carbonate / 4 h / 20 °C
3: sodium periodate; ruthenium(III) chloride*(x)H2O / tetrachloromethane; water; acetonitrile / 8 h / 20 °C
View Scheme
参考文献
Sugiyama, Shigeo; Arai, Satoshi; Ishii, Keitaro
Tetrahedron, 2012 , vol. 68, # 38 p. 8033 - 8045
反应条件
1: ammonia
2: hydrogenchloride; water
3: cinchonidine
4: dichloromethane / 72 h / 20 °C
View Scheme
参考文献
Drabina, Pavel; Karel, Sergej; Panov, Illia; Sedlak, Milos
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 334 - 339
反应条件
1: hydrogenchloride; water
2: cinchonidine
3: dichloromethane / 72 h / 20 °C
View Scheme
参考文献
Drabina, Pavel; Karel, Sergej; Panov, Illia; Sedlak, Milos
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 334 - 339
反应条件
1: cinchonidine
2: dichloromethane / 72 h / 20 °C
View Scheme
参考文献
Drabina, Pavel; Karel, Sergej; Panov, Illia; Sedlak, Milos
Tetrahedron Asymmetry, 2013 , vol. 24, # 5-6 p. 334 - 339
参考文献
Ayoub, Mimoun; Chassaing, Gerard; Loffet, Albert; Lavielle, Solange
Tetrahedron Letters, 1995 , vol. 36, # 23 p. 4069 - 4072
