2'-羟基-3',4'-二甲氧基苯乙酮合成路线 （共 32 条）
参考文献
v.Kostanecki; Rudse
Chemische Berichte, 1905 , vol. 38, p. 936
反应条件
1: 6.4 g / K2CO3 / acetone / Heating; overnight
2: 1.) Tl(NO3)3 on Montmorillinite clay; 2.) sodium methoxide; aq. HCl / 1.) methylene chloride, room temperature, 1 h; 2.) methanol, H2O, overnight
3: 94 percent / xylene / 18 h / Heating
4: POCl3 / toluene / 2 h / Heating
5: sodium acetate / Ambient temperature; overnight
6: 76 percent / H2 / 5percent Pd/CaCO3 / tetrahydrofuran / 6 h / Ambient temperature
View Scheme
参考文献
Lenz; Woo
Journal of Heterocyclic Chemistry, 1981 , vol. 18, # 4 p. 691 - 693
