9-氯-1,2,3,4-四氢吖啶合成路线 （共 28 条）
反应条件
1: 92 percent / K2CO3, KI / dimethylformamide / 24 h / Ambient temperature 2: 90 percent / 58 h / Heating 3: 76 percent / Ac2O, pyridine / 2 h / 140 °C 4: 90 percent / 10percent HCl / 1 h / Heating 5: POCl3 / 3 h / Heating View Scheme
参考文献
Heterocycles, , vol. 26, # 1 p. 191 - 197
反应条件
1: 67 percent / Dowtherm / 220 °C 2: 75 percent / POCl3 / Heating View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 6, # 24 p. 2999 - 3002
反应条件
1: 90 percent / 58 h / Heating 2: 76 percent / Ac2O, pyridine / 2 h / 140 °C 3: 90 percent / 10percent HCl / 1 h / Heating 4: POCl3 / 3 h / Heating View Scheme
参考文献
Heterocycles, , vol. 26, # 1 p. 191 - 197
反应条件
1: 90 percent / 10percent HCl / 1 h / Heating 2: POCl3 / 3 h / Heating View Scheme
参考文献
Heterocycles, , vol. 26, # 1 p. 191 - 197
反应条件
1: 76 percent / Ac2O, pyridine / 2 h / 140 °C 2: 90 percent / 10percent HCl / 1 h / Heating 3: POCl3 / 3 h / Heating View Scheme
参考文献
Heterocycles, , vol. 26, # 1 p. 191 - 197
参考文献
Journal of the Chemical Society, , vol. 125, p. 2449
Journal of the Chemical Society, , p. 440
反应条件
p-cresol; ammonia T=180°C;
参考文献
Albert; Gledhill
Journal of the Society of Chemical Industry, London, 1945 , vol. 64, p. 169,170
反应条件
sodium iodide; phenol T=180°C; 2 h;
参考文献
Szymanski; Zurek; Mikiciuk-Olasik, Elzbieta
Pharmazie, 2006 , vol. 61, # 4 p. 269 - 273
反应条件
{(S)-1-[(R)-(diphenylphosphino)ferrocenyl]}ethyl-di-tert-butylphosphine; palladium diacetate; sodium t-butanolate in ethylene glycol dimethyl ether T=100°C; 24 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 52, # 8 p. 916 - 919
反应条件
{(S)-1-[(R)-(diphenylphosphino)ferrocenyl]}ethyl-di-tert-butylphosphine; palladium diacetate; sodium t-butanolate in ethylene glycol dimethyl ether T=100°C; 18 h; Inert atmosphere;
参考文献
Tetrahedron Letters, , vol. 52, # 8 p. 916 - 919
