(e)-3-(3,4-二甲氧基苯基)-2-丙烯酸甲酯合成路线 （共 46 条）
反应条件
lithium hydroxide in tetrahydrofuran T=20°C;
参考文献
Jung, Mankil; Lee, Yongnam; Park, Moonsoo; Kim, Hanjo; Kim, Heekyeong; Lim, Eunyoung; Tak, Jungae; Sim, Minjoo; Lee, Dongeun; Park, Namsoo; Oh, Won Keun; Hur, Kyu Yeon; Kang, Eun Seok; Lee, Hyun-Chul
Bioorganic and Medicinal Chemistry Letters, 2007 , vol. 17, # 16 p. 4481 - 4486
反应条件
N-bromosuccinmide; 4 A molecular sieve; sodium hydrogencarbonate; Sm(OTf)3 in acetonitrile
T=15°C; Friedel-Crafts alkylation; 12 h;
参考文献
Hajra, Saumen; Maji, Biswajit; Bar, Sukanta
Organic Letters, 2007 , vol. 9, # 15 p. 2783 - 2786
反应条件
1: palladium; acetic acid / Hydrogenation
2: aqueous ammonia
View Scheme
参考文献
Kindler; Peschke
Archiv der Pharmazie (Weinheim, Germany), 1932 , vol. 270, p. 353,359
反应条件
1: CHCl3; bromine
2: acetic acid
View Scheme
参考文献
Adler; Bjoerkqvist
Acta Chemica Scandinavica (1947-1973), 1951 , vol. 5, p. 241,247
反应条件
sodium hydrogencarbonate; 3-chloro-benzenecarboperoxoic acid in dichloromethane; water
24 h; Heating;
参考文献
Moyna, Guillermo; Williams, Howard J.; Scott
Synthetic Communications, 1996 , vol. 26, # 11 p. 2235 - 2239
反应条件
sodium hydrogencarbonate in dichloromethane; water
1.5 h; Ambient temperatureother methyl cinnamate derivatives, other temperatures, other reaction times, sodium bicarbonate and water absence; Product distributionMechanism;
参考文献
Moyna, Guillermo; Williams, Howard J.; Scott
Synthetic Communications, 1996 , vol. 26, # 11 p. 2235 - 2239
