1-氯-3-苯基-2-丙醇合成路线 (共 21 条)
反应条件
1: 74 percent / m-chloroperbenzoic acid / CH2Cl2 / Ambient temperature
2: 26 percent / PdCl2(MeCN)2, CuCl2, air / CH2Cl2 / 120 h / Ambient temperature; Irradiation
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参考文献
Muzart, Jacques; Riahi, Abdelkhalek
Journal of Organometallic Chemistry, 1992 , vol. 433, # 3 p. 323 - 336
反应条件
sodium tetrahydroborate; sodium hydrogencarbonate in ethanol; water
1 h; Yield given;
参考文献
Barluenga, Jose; Florez, Josefa; Yus, Miguel
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 3019 - 3026
反应条件
1: diethyl ether / 2 h / -20 - 0 °C
2: NaBH4, NaHCO3 / ethanol; H2O / 1 h
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参考文献
Barluenga, Jose; Florez, Josefa; Yus, Miguel
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), 1983 , # 12 p. 3019 - 3026
反应条件
nickel dichloride in hexane
T=35°C; 2 h; other Al compounds, catalyst, solvents, further epoxides; Product distribution;
参考文献
Boireau, G.; Abenhaim, D.; Henry-Basch, E.
Tetrahedron, 1980 , vol. 36, p. 3061 - 3070
反应条件
in water
48 h; Mechanism;
参考文献
Rav-Acha, Chaim; Choshen, Ehud; Sarel, Shalom
Helvetica Chimica Acta, 1986 , vol. 69, p. 1728 - 1733
参考文献
Tapia; Hernandez
Chem. Zentralbl., 1930 , vol. 101, # II p. 1697
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Riedel
Chem. Zentralbl., 1907 , vol. 78, # I p. 1607
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Riedel
Patent: DE183361 ;
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Fourneau; Tiffeneau
Bulletin de la Societe Chimique de France, 1907 , vol. <4> 1, p. 1228
反应条件
1: Na2Cr2O7, H2SO4 / acetone
2: diethyl ether
3: NaI / acetone / Heating
View Scheme
参考文献
Galons; Girardeau; Combet Farnoux; et al.
European Journal of Medicinal Chemistry, 1979 , vol. 14, # 2 p. 165 - 170
反应条件
phosphorus pentachloride
参考文献
Seberg
Zhurnal Obshchei Khimii, 1935 , vol. 5, p. 1016
Chem. Zentralbl., 1936 , vol. 107, # I p. 2913
参考文献
Fourneau; Tiffeneau
Bulletin de la Societe Chimique de France, 1907 , vol. <4> 1, p. 1228
反应条件
(i) phthalimide <K salt>, DMF, (ii) N2H4*H2O, MeOH, (iii) aq. HCl; Multistep reaction;
参考文献
Adlerova,E. et al.
Collection of Czechoslovak Chemical Communications, 1969 , vol. 34, p. 479 - 484