1,5-二苯基-3-戊酮合成路线 （共 80 条）
反应条件
1: benzene
2: platinum / Hydrogenation
View Scheme
参考文献
Nightingale; Wadsworth
Journal of the American Chemical Society, 1947 , vol. 69, p. 1181
Journal of the American Chemical Society, 1945 , vol. 67, p. 416
反应条件
1: benzene
2: platinum / Hydrogenation
View Scheme
参考文献
Nightingale; Wadsworth
Journal of the American Chemical Society, 1947 , vol. 69, p. 1181
Journal of the American Chemical Society, 1945 , vol. 67, p. 416
反应条件
1: 81 percent / diethyl ether / 1 h / 0 °C
2: 93 percent / Jones reagent / acetone / 0.17 h / 0 °C
View Scheme
参考文献
Ueki, Hisanori; Chiba, Takashi; Yamazaki, Takashi; Kitazume, Tomoya
Journal of Organic Chemistry, 2004 , vol. 69, # 22 p. 7616 - 7627
反应条件
potassium; carbon in tetrahydrofuran
参考文献
Savoia,D. et al.
Journal of Organic Chemistry, 1978 , vol. 43, p. 2907 - 2910
反应条件
lithium diisopropyl amide
1. THF, -70 deg C, 15 min 2. 10 s; Yield given. Multistep reaction;
参考文献
Inoue, Tan; Sato, Toshio; Kuwajima, Isao
Journal of Organic Chemistry, 1984 , vol. 49, # 24 p. 4671 - 4674
反应条件
N-bromosuccinmide in water; acetone
参考文献
Seebach,D.
Synthesis, 1969 , p. 17 - 36
反应条件
hydrogenchloride; palladium
Hydrogenation;
参考文献
Weidlich; Meyer-Delius
Chemische Berichte, 1941 , vol. 74, p. 1195,1209
反应条件
tert.-butyl lithium in diethyl ether
参考文献
Kaplan,E.P. et al.
J. Gen. Chem. USSR (Engl. Transl.), 1963 , vol. 33, # 7 p. 2103 - 2106,2048 - 2051
反应条件
1.1: magnesium / tetrahydrofuran / 2 h / 50 °C / |Inert atmosphere
1.2: 50 °C / |Inert atmosphere
2.1: Jone's reagent / acetone / |Cooling with ice
View Scheme
参考文献
Zhang, Qian-Chong; Wu, Fang-Ting; Hao, Hui-Min; Xu, Hang; Zhao, Hai-Xia; Long, La-Sheng; Huang, Rong-Bin; Zheng, Lan-Sun
Angewandte Chemie - International Edition, 2013 , vol. 52, # 48 p. 12602 - 12605
Angew. Chem., 2013 , p. 12834 - 12837,4
反应条件
(i) KNH2, liq. NH3, THF, (ii) /BRN= 471308/, (iii) (hydrolysis); Multistep reaction;
参考文献
Harris,T.M. et al.
Journal of the American Chemical Society, 1963 , vol. 85, p. 3273 - 3276
