1,5-二苯基-3-戊酮合成路线 （共 80 条）
反应条件
1: N2H4+H2O; KOH; diethylene glycol
2: AlCl3
View Scheme
参考文献
Allinger; Cram
Journal of the American Chemical Society, 1954 , vol. 76, p. 2362,2367
反应条件
1: 1-bromo-1-trimethylsilylethene With tert.-butyl lithium in diethyl ether; pentane
T=-78°C;
2: 1,5-Diphenylpentan-3-one in diethyl ether; pentane
T=0°C;
3: in diethyl ether; N,N-dimethyl-formamide; pentane
T=80°C; Peterson allenation; Further stages.;
参考文献
Tsubouchi, Akira; Kira, Takashiro; Takeda, Takeshi
Synlett, 2006 , # 16 p. 2577 - 2580
反应条件
1: C14H21BrSi With tert.-butyl lithium in diethyl ether; pentane
T=-78°C;
2: 1,5-Diphenylpentan-3-one in diethyl ether; pentane
T=-78 - 0°C;
3: in diethyl ether; N,N-dimethyl-formamide; pentane
T=80°C; Peterson allenation; Further stages.;
参考文献
Tsubouchi, Akira; Kira, Takashiro; Takeda, Takeshi
Synlett, 2006 , # 16 p. 2577 - 2580
参考文献
Abbott Laboratories
Patent: US5142056 A1, 1992 ;
US 5142056 A
反应条件
3-methyl-2-amino-pyridine; Wilkinson's catalyst
T=150°C; 48 h;
参考文献
Jun, Chul-Ho; Lee, Hyuk
Journal of the American Chemical Society, 1999 , vol. 121, # 4 p. 880 - 881
反应条件
[(η5-C5Me5)2Rh2(μ-Cl)2Cl2]; oxygen; potassium hydroxide in methanol
T=65°C; 48 h; Sealed tube;
参考文献
Chan, Louis K. M.; Poole, Darren L.; Shen, Di; Healy, Mark P.; Donohoe, Timothy J.
Angewandte Chemie - International Edition, 2014 , vol. 53, # 3 p. 761 - 765
Angew. Chem., 2014 , vol. 126, # 3 p. 908
反应条件
(i) NaH, THF, (ii) /BRN= 2052819/; Multistep reaction;
参考文献
Dinizo,S.E. et al.
Journal of Organic Chemistry, 1976 , vol. 41, # 17 p. 2846 - 2849
反应条件
1: N2H4+H2O; KOH; diethylene glycol
2: AlCl3
View Scheme
参考文献
Allinger; Cram
Journal of the American Chemical Society, 1954 , vol. 76, p. 2362,2367
反应条件
hydrogenchloride; ethanol; hydroxylamine hydrochloride; water
参考文献
Weidlich; Meyer-Delius
Chemische Berichte, 1941 , vol. 74, p. 1195,1209
Full Text Show Details
Nightingale; Wadsworth
Journal of the American Chemical Society, 1947 , vol. 69, p. 1181
Journal of the American Chemical Society, 1945 , vol. 67, p. 416
参考文献
Ipatjew; Orlow
Comptes Rendus Hebdomadaires des Seances de l'Academie des Sciences, 1927 , vol. 184, p. 753
Bulletin de la Societe Chimique de France, 1927 , vol. <4> 41, p. 864
Full Text Show Details
Ipatjew; Orlow
Zhurnal Russkago Fiziko-Khimicheskago Obshchestva, 1927 , vol. 59, p. 538
