2-(6-溴己氧基)四氢-2H-吡喃合成路线 （共 75 条）
反应条件
camphor-10-sulfonic acid in dichloromethane T=0°C; 2 h;
参考文献
Morimoto, Yoshiki; Kitao, Satoru; Okita, Tatsuya; Shoji, Takamasa
Organic Letters, 2003 , vol. 5, # 15 p. 2611 - 2614
反应条件
2,6-dimethylpyridine; tetraethylammonium bromide; Xtalfluor-E® in dichloromethane T=21°C; Inert atmosphere;
参考文献
Pouliot, Marie-France; Mahe, Olivier; Hamel, Jean-Denys; Desroches, Justine; Paquin, Jean-Francois
Organic Letters, 2012 , vol. 14, # 21 p. 5428 - 5431,4
反应条件
1: aq. HBr / 40 h / 80 °C 2: aq. HCl / 16 h / 20 °C View Scheme
参考文献
Bioscience, Biotechnology and Biochemistry, , vol. 69, # 7 p. 1348 - 1352
反应条件
sodium bromide; 1,1-dibromomethane in N,N-dimethyl-formamide T=100°C; 4 h;
参考文献
Babler, James H.; Spina, Kenneth P.
Synthetic Communications, 1984 , vol. 14, # 14 p. 1313 - 1320
反应条件
pyridinium p-toluenesulfonate in dichloromethane T=20°C; 3 h; Inert atmosphere;
参考文献
Besse; Le Pluart; Cook; Pham; Madec
Journal of Polymer Science, Part A: Polymer Chemistry, 2013 , vol. 51, # 1 p. 149 - 157
反应条件
4-(bromomethylene)morpholin-4-ium bromide in dichloromethane T=0°C; 1.5 h; Inert atmosphere;
参考文献
Synthesis, , # 22 p. 3565 - 3568
反应条件
2: CBr3, PPh3 View Scheme
参考文献
Bioorganic and Medicinal Chemistry Letters, , vol. 7, # 11 p. 1365 - 1370
反应条件
1: 99 percent / p-toluenesulfonic acid monohydrate / CH2Cl2 / 1.5 h / 20 °C 2: 86 percent / NaBr, dibromomethane / dimethylformamide / 4 h / 100 °C View Scheme
参考文献
Synthetic Communications, , vol. 14, # 14 p. 1313 - 1320
反应条件
1: 80 percent / HBr / ethanol / 4 h 2: 66 percent / LAH / diethyl ether / 3 h / -78 °C 3: 75 percent / conc.HCl / 5 h / Ambient temperature View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 1081 - 1083
反应条件
1: 66 percent / LAH / diethyl ether / 3 h / -78 °C 2: 75 percent / conc.HCl / 5 h / Ambient temperature View Scheme
参考文献
Indian Journal of Chemistry, Section B: Organic Chemistry Including Medicinal Chemistry, , vol. 24, p. 1081 - 1083
