2-碘-3-硝基-苯甲酸合成路线 （共 24 条）
反应条件
1: tin (II)-chloride; aqueous hydrochloric acid; ethanol 2: aqueous hydrogen fluoride / Behandeln der erhaltenen Suspension mit Natriumnitrit View Scheme
参考文献
Stanley; McMahon; Adams
Journal of the American Chemical Society, 1933 , vol. 55, p. 706,712
参考文献
Arnone, Caterina; Consiglio, Giovanni; Frenna, Vincenzo; Spinelli, Domenico
Journal of Organic Chemistry, 1997 , vol. 62, # 10 p. 3093 - 3097
反应条件
sulfuric acid 48 h; Heating;
参考文献
Takeda Pharmaceutical Company Limited
Patent: EP2141150 A1, 2010 ;
Location in patent: Page/Page column 103-104 ;
反应条件
sulfuric acid; trimethyl orthoformate in methanol
参考文献
Agouron Pharmaceuticals, Inc.
Patent: US6495541 B1, 2002 ;
参考文献
Iffland; Siegel
Journal of the American Chemical Society, 1958 , vol. 80, p. 1947,1949
反应条件
1: 26 percent 2: 93 percent / H2O2 / acetic acid 3: 92 percent / acetic acid; acetic anhydride 4: m-chloroperbenzoic acid / CHCl3 View Scheme
参考文献
Liebigs Annalen der Chemie, , # 1 p. 14 - 27
反应条件
1: 95 percent / H2SO4 / 48 h / Heating 2: 28 percent / CuI; iPr2NH / Pd(PPh3)2Cl2 / tetrahydrofuran / 48 h / 45 °C View Scheme
参考文献
Woon, Esther C.Y.; Dhami, Archana; Mahon, Mary F.; Threadgill, Michael D.
Tetrahedron, 2006 , vol. 62, # 20 p. 4829 - 4837
反应条件
hydrogenchloride; acetic acid; tin(ll) chloride Diazotieren des Reaktionsprodukts und anschliessendes Behandeln mit CuCl und konz. wss. HCl;
参考文献
Twiss; Heinzelmann
Journal of Organic Chemistry, 1950 , vol. 15, p. 496,508
反应条件
potassium hydroxide; copper
参考文献
Pelz,K. et al.
Collection of Czechoslovak Chemical Communications, 1968 , vol. 33, # 6 p. 1852 - 1872
反应条件
1: phenylacetylene With ammonium hydroxide; copper(l) iodide in ethanol 0.25 h; 2: 2-iodo-3-nitrobenzoic acid With pyridine Castro-Stephen coupling; 6 h; Heating;
参考文献
Tetrahedron, , vol. 62, # 20 p. 4829 - 4837
