2-氨基-5-氟苯酚合成路线

参考文献

GLAXO GROUP LIMITED; GORE, Paul Martin; HANCOCK, Ashley, Paul; HODGSON, Simon Teanby
Patent: WO2010/94643 A1, 2010 ;
Location in patent: Page/Page column 46 ;
WO 2010/094643 A1

127682-43-3

372-20-33-氟苯酚+

399-95-14-氨基-3-氟苯酚+

53981-24-12-氨基-5-氟苯酚+

53981-23-02-氨基-3-氟苯酚

参考文献

Journal of the American Chemical Society, , vol. 114, # 25 p. 9795 - 9806

123-73-9巴豆醛+

53981-24-12-氨基-5-氟苯酚

1070897-08-3

参考文献

WO2012/154274 A1, ;

Page/Page column 118 ;
WO 2012/154274 A1

53981-24-12-氨基-5-氟苯酚+

78-39-7原乙酸三乙酯

312600-96-7

参考文献

GE HEALTHCARE UK LIMITED
Patent: WO2008/40994 A2, 2008 ;
Location in patent: Page/Page column 24-25 ;

140-89-6乙基黄原酸钾+

53981-24-12-氨基-5-氟苯酚

145096-57-7

参考文献

PIERRE FABRE MEDICAMENT; Dupont-Passelaigue, Elisabeth; Le Roy, Isabelle; Pignier, Christophe
Patent: US2013/172326 A1, 2013 ;
Location in patent: Paragraph 0067; 0068 ;

75-15-0二硫化碳+

53981-24-12-氨基-5-氟苯酚

145096-57-7

参考文献

Ouyang, Liang; Huang, Yuhui; Zhao, Yuwei; He, Gu; Xie, Yongmei; Liu, Jie; He, Jun; Liu, Bo; Wei, Yuquan
Bioorganic and Medicinal Chemistry Letters, 2012 , vol. 22, # 9 p. 3044 - 3049

53981-24-12-氨基-5-氟苯酚+

106-93-4二溴乙烷

56346-41-9

参考文献

EP2172453 A1, ;

Page/Page column 14-15 ;
EP 2172453 A1

53981-24-12-氨基-5-氟苯酚+

79-04-9一氯代乙酰氯

103361-99-5

参考文献

Bioorganic and Medicinal Chemistry Letters, , vol. 18, # 16 p. 4700 - 4704

53981-24-12-氨基-5-氟苯酚

134894-49-8

参考文献

Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897

53981-24-12-氨基-5-氟苯酚

140413-12-3

参考文献

Klunder, Janice M.; Hargrave, Karl D.; West, MaryAnn; Cullen, Ernest; Pal, Kollol; et al.
Journal of Medicinal Chemistry, 1992 , vol. 35, # 10 p. 1887 - 1897