异烟肼合成路线 - 魔法化学

Zampieri, Daniele; Mamolo, Maria Grazia; Laurini, Erik; Fermeglia, Maurizio; Posocco, Paola; Pricl, Sabrina; Banfi, Elena; Scialino, Giuditta; Vio, Luciano
Bioorganic and Medicinal Chemistry, 2009 , vol. 17, # 13 p. 4693 - 4707

75-44-5光气+

54-85-3异烟肼

2845-82-15-(吡啶-4-基)-1,3,4-噁二唑-2(3H)-酮

参考文献

Geistlich Soehne A.G.
Patent: US2758117 , 1954 ;

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Geistlich Soehne A.G.
Patent: DE1001683 , 1954 ;

54-85-3异烟肼

2845-82-15-(吡啶-4-基)-1,3,4-噁二唑-2(3H)-酮

参考文献

Yan, Xu; Zhou, Shuo; Wang, Yuanqiang; Ge, Zemei; Cheng, Tieming; Li, Runtao
Tetrahedron, 2012 , vol. 68, # 38 p. 7978 - 7983

2845-82-15-(吡啶-4-基)-1,3,4-噁二唑-2(3H)-酮

参考文献

Yale et al.
Journal of the American Chemical Society, 1954 , vol. 76, p. 2208,2210
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Taniyama et al.
Yakugaku Zasshi, 1956 , vol. 76, p. 1304,1306, 1307
Chem.Abstr., 1957 , p. 4275

75-44-5光气+

54-85-3异烟肼+

7732-18-5水

2845-82-15-(吡啶-4-基)-1,3,4-噁二唑-2(3H)-酮

参考文献

Hoffmann-La Roche
Patent: US2665279 , 1952 ;

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Koenig et al.
Chemische Berichte, 1954 , vol. 87, p. 825,834
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Farbenfabr. Bayer
Patent: DE923722 , 1952 ;

7647-01-0盐酸+

75-44-5光气+

54-85-3异烟肼

2845-82-15-(吡啶-4-基)-1,3,4-噁二唑-2(3H)-酮

参考文献

Caldwell et al.
Journal of the American Pharmaceutical Association (1912-1977), 1958 , vol. 47, p. 799,801, 802

54-85-3异烟肼

54-92-2异烟酸2-异丙基酰肼

参考文献

Yale et al.
Journal of the American Chemical Society, 1953 , vol. 75, p. 1933,1934
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McMillan et al.
Journal of the American Pharmaceutical Association (1912-1977), 1953 , vol. 42, p. 457,463