2-氨基-6-(甲基氨基)-4-嘧啶醇合成路线 (共 2 条)
反应条件
acetic acid; sodium nitrite in water
T=25°C; 1 h;
参考文献
Lever, O. William; Bell, Lawrence N.; McGuire, H. Michael; Ferone, Robert
Journal of Medicinal Chemistry, 1985 , vol. 28, # 12 p. 1870 - 1874
反应条件
potassium carbonate in methanol
1 h; Heating / reflux;
参考文献
TAKEDA PHARMACEUTICAL COMPANY LIMITED
Patent: WO2005/99688 A2, 2005 ;
Location in patent: Page/Page column 315 ;
WO 2005/099688 A2