N-(3,4-二氯苯基)马来酸合成路线 （共 3 条）
反应条件
sodium acetate in acetic anhydride T=20 - 100°C; 0.5 h;
参考文献
Budke, Brian; Kalin, Jay H.; Pawlowski, Michal; Zelivianskaia, Anna S.; Wu, Megan; Kozikowski, Alan P.; Connell, Philip P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 1 p. 254 - 263
反应条件
in diethyl ether
T=20°C; 2 h;
参考文献
Budke, Brian; Kalin, Jay H.; Pawlowski, Michal; Zelivianskaia, Anna S.; Wu, Megan; Kozikowski, Alan P.; Connell, Philip P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 1 p. 254 - 263
反应条件
1: sodium acetate / acetic anhydride / 0.5 h / 20 - 100 °C
2: thionyl chloride; pyridine / 1.25 h / 0 °C / |Reflux
View Scheme
参考文献
Budke, Brian; Kalin, Jay H.; Pawlowski, Michal; Zelivianskaia, Anna S.; Wu, Megan; Kozikowski, Alan P.; Connell, Philip P.
Journal of Medicinal Chemistry, 2013 , vol. 56, # 1 p. 254 - 263
