potassium hydroxide in ethanol 0.5 h; Reflux;

potassium acetate; palladium diacetate in N,N-dimethyl acetamide T=130°C; 20 h; Inert atmosphere; regioselective reaction;

1: 3-trifluoromethyl-aniline With hydrogenchloride; sodium nitrite 2: furan-5alpha-carboxylic acid methyl ester With CuCl2*2H2O in water; acetone T=0 - 30°C;