5-(2-氨基苯基)-呋喃-2-羧酸乙酯合成路线 （共 4 条）
反应条件
hydrogen; palladium on activated charcoal in methanol
T=20°C; P=2280 Torr; 2 h;
参考文献
Lee, Sunkyung; Yi, Kyu Yang; Hwang, Sun Kyung; Lee, Byung Ho; Yoo, Sung-Eun; Lee, Kyunghee
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2882 - 2891
反应条件
1: 94 percent / Pd(PPh3)4; aq. Na2CO3 / toluene; methanol / 6 h / Heating
2: 94 percent / H2 / Pd/C / methanol / 2 h / 20 °C / 2280 Torr
View Scheme
参考文献
Lee, Sunkyung; Yi, Kyu Yang; Hwang, Sun Kyung; Lee, Byung Ho; Yoo, Sung-Eun; Lee, Kyunghee
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2882 - 2891
反应条件
1: 94 percent / Pd(PPh3)4; aq. Na2CO3 / toluene; methanol / 6 h / Heating
2: 94 percent / H2 / Pd/C / methanol / 2 h / 20 °C / 2280 Torr
View Scheme
参考文献
Lee, Sunkyung; Yi, Kyu Yang; Hwang, Sun Kyung; Lee, Byung Ho; Yoo, Sung-Eun; Lee, Kyunghee
Journal of Medicinal Chemistry, 2005 , vol. 48, # 8 p. 2882 - 2891
反应条件
hydrogenchloride; sulfur dioxide; ammonia; sodium nitrite; Copper(I)chloride in (2S)-N-methyl-1-phenylpropan-2-amine hydrate; n-butyl chloride; water; acetic acid
参考文献
E. I. Du Pont de Nemours and Company
Patent: US4460401 A1, 1984 ;
