6-氨基-2-甲基硫代-3-甲基尿嘧啶合成路线 （共 9 条）
反应条件
potassium carbonate in N,N-dimethyl-formamide T=80 - 85°C; 4 h;
参考文献
Journal of Medicinal Chemistry, , vol. 51, # 6 p. 1764 - 1770
反应条件
ethanol; sodium ethanolate
参考文献
American Chemical Journal, , vol. 34, p. 190
Journal of Biological Chemistry, , vol. 20, p. 158
反应条件
sodium hydroxide T=40°C; 1 h; Yield given. Yields of byproduct given;
参考文献
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, , vol. 52, # 12 p. 1526 - 1532
参考文献
Journal of Biological Chemistry, , vol. 20, p. 158
反应条件
1: 91 percent / 1N aq. NaOH / 2 h / Heating 2: 95 percent / aq. NaOAc, AcOH, NaNO2 / 0.5 h / 100 °C 3: 82 percent / H2, NaOH / 10percent Pd/C / methanol; H2O / 20 °C / 2625.2 Torr 4: 97 percent / NaOAc, glacial AcOH / 3 h / Heating View Scheme
参考文献
Roehrkasten; Raatz; Kreher; Blaszkewicz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1997 , vol. 52, # 12 p. 1526 - 1532
反应条件
1: 91 percent / 1N aq. NaOH / 2 h / Heating 2: 95 percent / aq. NaOAc, AcOH, NaNO2 / 0.5 h / 100 °C View Scheme
参考文献
Roehrkasten; Raatz; Kreher; Blaszkewicz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1997 , vol. 52, # 12 p. 1526 - 1532
反应条件
sodium hydroxide 2 h; Heating;
参考文献
Roehrkasten; Raatz; Kreher; Blaszkewicz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1997 , vol. 52, # 12 p. 1526 - 1532
反应条件
isopentyl nitrite in dimethyl sulfoxide
T=20°C; 1 h;
参考文献
Marchal, Antonio; Melguizo, Manuel; Nogueras, Manuel; Sanchez, Adolfo; Low, John N.
Synlett, 2002 , # 2 p. 255 - 258
反应条件
1: 91 percent / 1N aq. NaOH / 2 h / Heating
2: 95 percent / aq. NaOAc, AcOH, NaNO2 / 0.5 h / 100 °C
3: 82 percent / H2, NaOH / 10percent Pd/C / methanol; H2O / 20 °C / 2625.2 Torr
View Scheme
参考文献
Roehrkasten; Raatz; Kreher; Blaszkewicz
Zeitschrift fur Naturforschung - Section B Journal of Chemical Sciences, 1997 , vol. 52, # 12 p. 1526 - 1532
