1.1: 95 percent / Raney-Ni; hydrogen / methanol / 18 h / 20 °C / 760 Torr 2.1: TBAF / tetrahydrofuran / 6 h / 20 °C 2.2: NaClO2; TEMPO; aqueous NaH2PO4 buffer / NaClO / H2O; acetonitrile / 24 h / 45 °C / pH 6.6 View Scheme

1: 81 percent / TBAF / tetrahydrofuran / 6 h / 20 °C 2: 93 percent / Ir(COD)PyPCy3PF6; hydrogen / CH2Cl2 / 18 h / 20 °C / 760 Torr 3: 86 percent / NaClO2; TEMPO; aqueous NaH2PO4 buffer / NaClO / H2O; acetonitrile / 24 h / 45 °C / pH 6.6 View Scheme