3-(4-甲氧苯基)-1-丙醇合成路线 （共 74 条）
反应条件
methanol; formic acid; water; silica gel; palladium dichloride 0.9 h; Irradiationmicrowave;
参考文献
Advanced Synthesis and Catalysis, , vol. 348, # 3 p. 354 - 360
反应条件
1.1: 100 percent / diethyl ether; methanol / 24 h / 10 °C 2.1: O3 / CH2Cl2; methanol / -78 °C 2.2: 73 percent / Ph3P / CH2Cl2; methanol / 0.5 h 3.1: 76 percent / CH2Cl2 / 5 h / Heating 4.1: H2 / 10 percent Pd/C / ethyl acetate / 20 °C 4.2: 76 percent / LiAlH4 / tetrahydrofuran / 5 h / Heating View Scheme
参考文献
Journal of agricultural and food chemistry, , vol. 50, # 10 p. 2748 - 2754
反应条件
1: 50.6 percent / LiAlH4 / tetrahydrofuran / 6 h / Heating 2: 94.9 percent / K2CO3 / acetone View Scheme
参考文献
Journal of Medicinal Chemistry, , vol. 45, # 12 p. 2358 - 2361
反应条件
1: 1.) aluminium chloride, 2.) sodium dithionite, sodium hydroxide / 1.) 1,1,2,2-tetrachloroethane, room temperature, 16 h; steam-bath, 2 h, 2.) methanol, room temperature, 21 h, reflux, 24 h 2: 88 percent / hydrogen / palladium-carbon / acetic acid / 1.5 h / Ambient temperature 3: 59 percent / lithium aluminium hydride / diethyl ether 4: 62 percent / pyridine 5: 80 percent / lithium bromide / acetone / 24 h / Ambient temperature 6: magnesium (from magnesium chloride and potassium metal, 3-(4-methoxyphenyl)propanal / tetrahydrofuran View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 614 - 622
反应条件
1: 88 percent / hydrogen / palladium-carbon / acetic acid / 1.5 h / Ambient temperature 2: 59 percent / lithium aluminium hydride / diethyl ether 3: 62 percent / pyridine 4: 80 percent / lithium bromide / acetone / 24 h / Ambient temperature 5: magnesium (from magnesium chloride and potassium metal, 3-(4-methoxyphenyl)propanal / tetrahydrofuran View Scheme
参考文献
Journal of the Chemical Society, Perkin Transactions 1: Organic and Bio-Organic Chemistry (1972-1999), , p. 614 - 622
反应条件
1: With potassium fluoride; potassium hydrogencarbonate in tetrahydrofuran; methanol T=20°C; Tamao oxidation; 1 h; In air; 2: With dihydrogen peroxide in tetrahydrofuran; methanol; water T=20°C; Tamao oxidation;
参考文献
Synlett, , # 19 art. no. D28811ST, p. 2811 - 2814
反应条件
1: With benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride in dichloromethane T=20°C; 0.5 h; 2: With sodium tetrahydroborate; cerium(III) chloride; water in tetrahydrofuran T=0°C; 0.5 h;
参考文献
Synthesis, , # 9 art. no. M12811SS, p. 1375 - 1382
反应条件
(i) NaBH4, BF3-Et2O, diglyme, (ii) aq. H2O2, NaOH; Multistep reaction;
参考文献
Tetrahedron, , vol. 22, p. 861 - 866
反应条件
bis-(trifluoromethylsulphonyl)amine Electrochemical reactionIonic liquid;
参考文献
Meng, Yao; Aldous, Leigh; Pilgrim, Ben S.; Donohoe, Timothy J.; Compton, Richard G.
New Journal of Chemistry, 2011 , vol. 35, # 7 p. 1369 - 1375
反应条件
1: 79 percent / sulfuric acid / 4 h 2: 94 percent / LiAlH4 / tetrahydrofuran / 16 h / Heating View Scheme
参考文献
Indian Journal of Chemistry - Section B Organic and Medicinal Chemistry, , vol. 44, # 2 p. 372 - 375
